| http://purl.uniprot.org/citations/23563688 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23563688 | http://www.w3.org/2000/01/rdf-schema#comment | "Here we identified B cells as a major source of rapid, innate-like production of interleukin 17 (IL-17) in vivo in response to infection with Trypanosoma cruzi. IL-17(+) B cells had a plasmablast phenotype, outnumbered cells of the TH17 subset of helper T cells and were required for an optimal response to this pathogen. With both mouse and human primary B cells, we found that exposure to parasite-derived trans-sialidase in vitro was sufficient to trigger modification of the cell-surface mucin CD45, which led to signaling dependent on the kinase Btk and production of IL-17A or IL-17F via a transcriptional program independent of the transcription factors RORγt and Ahr. Our combined data suggest that the generation of IL-17(+) B cells may be a previously unappreciated feature of innate immune responses required for pathogen control or IL-17-mediated autoimmunity."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni.2569"xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Campetella O."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Singh A.K."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Mucci J."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Khim S."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Rawlings D.J."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Oukka M."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Liggitt D."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Jackson S.W."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Gruppi A."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Acosta-Rodriguez E.V."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Sather B.D."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Amezcua-Vesely M.C."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Bermejo D.A."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/author | "Gorosito-Serran M."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/name | "Nat Immunol"xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/pages | "514-522"xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/title | "Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORgammat and Ahr that leads to IL-17 production by activated B cells."xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/23563688 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23563688 |
| http://purl.uniprot.org/citations/23563688 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23563688 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YWF2-mappedCitation-23563688 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23563688 |