| http://purl.uniprot.org/citations/23583447 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23583447 | http://www.w3.org/2000/01/rdf-schema#comment | "CIZ1 is a nuclear protein involved in DNA replication and is also implicated in human diseases including cancers. To gain an insight into its function in vivo, we generated mice lacking Ciz1. Ciz1-deficient (Ciz1(-/-)) mice grew without any obvious abnormalities, and Ciz1(-/-) mouse embryonic fibroblasts (MEFs) did not show any defects in cell cycle status, cell growth, and DNA damage response. However, Ciz1(-/-) MEFs were sensitive to hydroxyurea-mediated replication stress and susceptible to oncogene-induced cellular transformation. In addition, Ciz1(-/-) mice developed various types of leukemias by retroviral insertional mutagenesis. These results indicate that CIZ1 functions as a tumor suppressor in vivo."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2013.03.034"xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/author | "Ueda T."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/author | "Wolff L."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/author | "Ohtsubo M."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/author | "Watanabe W."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/author | "Yamasaki N."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/author | "Honda H."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/author | "Koller R."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/author | "Honda Z."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/author | "Nishibe R."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/pages | "1529-1535"xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/title | "CIZ1, a p21Cip1/Waf1-interacting protein, functions as a tumor suppressor in vivo."xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://purl.uniprot.org/core/volume | "587"xsd:string |
| http://purl.uniprot.org/citations/23583447 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23583447 |
| http://purl.uniprot.org/citations/23583447 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23583447 |
| http://purl.uniprot.org/uniprot/#_A0A0A0MQJ7-mappedCitation-23583447 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23583447 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YVQ0-mappedCitation-23583447 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23583447 |
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| http://purl.uniprot.org/uniprot/#_F6XWQ4-mappedCitation-23583447 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23583447 |
| http://purl.uniprot.org/uniprot/#_F7AT58-mappedCitation-23583447 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23583447 |
| http://purl.uniprot.org/uniprot/#_F7BM53-mappedCitation-23583447 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23583447 |