| http://purl.uniprot.org/citations/23602568 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23602568 | http://www.w3.org/2000/01/rdf-schema#comment | "Cellular information processing via reversible protein phosphorylation requires tight control of the localization, activity, and substrate specificity of protein kinases, which to a large extent is accomplished by complex formation with other proteins. Despite their critical role in cellular regulation and pathogenesis, protein interaction information is available for only a subset of the 518 human protein kinases. Here we present a global proteomic analysis of complexes of the human CMGC kinase group. In addition to subgroup-specific functional enrichment and modularity, the identified 652 high-confidence kinase-protein interactions provide a specific biochemical context for many poorly studied CMGC kinases. Furthermore, the analysis revealed a kinase-kinase subnetwork and candidate substrates for CMGC kinases. Finally, the presented interaction proteome uncovered a large set of interactions with proteins genetically linked to a range of human diseases, including cancer, suggesting additional routes for analyzing the role of CMGC kinases in controlling human disease pathways."xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.celrep.2013.03.027"xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/author | "Aebersold R."xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/author | "Gstaiger M."xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/author | "Keskitalo S."xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/author | "Varjosalo M."xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/author | "Vichalkovski A."xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/author | "Nurkkala H."xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/author | "Van Drogen A."xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/name | "Cell Rep"xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/pages | "1306-1320"xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/title | "The protein interaction landscape of the human CMGC kinase group."xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://purl.uniprot.org/core/volume | "3"xsd:string |
| http://purl.uniprot.org/citations/23602568 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23602568 |
| http://purl.uniprot.org/citations/23602568 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23602568 |
| http://purl.uniprot.org/uniprot/#_P10398-mappedCitation-23602568 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23602568 |
| http://purl.uniprot.org/uniprot/#_P11047-mappedCitation-23602568 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23602568 |
| http://purl.uniprot.org/uniprot/#_P15311-mappedCitation-23602568 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23602568 |
| http://purl.uniprot.org/uniprot/#_P56545-mappedCitation-23602568 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23602568 |
| http://purl.uniprot.org/uniprot/#_P61758-mappedCitation-23602568 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23602568 |
| http://purl.uniprot.org/uniprot/#_P61769-mappedCitation-23602568 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23602568 |
| http://purl.uniprot.org/uniprot/#_Q07955-mappedCitation-23602568 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23602568 |
| http://purl.uniprot.org/uniprot/#_Q14157-mappedCitation-23602568 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23602568 |