http://purl.uniprot.org/citations/23611113 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23611113 | http://www.w3.org/2000/01/rdf-schema#comment | "Nectin-like molecule 4 (Necl-4)/CADM4, a transmembrane cell-cell adhesion molecule with three Ig-like domains, was shown to serve as a tumor suppressor, but its mode of action has not been elucidated. In this study, we showed that Necl-4 interacted in cis with ErbB3 through their extracellular regions, recruited PTPN13 and inhibited the heregulin-induced activation of the ErbB2/ErbB3 signaling. In addition, we extended our previous finding that Necl-4 interacts in cis with integrin α6 β4 through their extracellular regions and found that Necl-4 inhibited the phorbol ester-induced disassembly of hemidesmosomes. These results indicate that Necl-4 serves as a tumor suppressor by inhibiting the ErbB2/ErbB3 signaling and hemidesmosome disassembly."xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.org/dc/terms/identifier | "doi:10.1111/gtc.12056"xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/author | "Takai Y."xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/author | "Shimono Y."xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/author | "Sugiyama H."xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/author | "Kurita S."xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/author | "Mizutani K."xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/author | "Okimoto N."xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/name | "Genes Cells"xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/pages | "519-528"xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/title | "Interaction of Necl-4/CADM4 with ErbB3 and integrin alpha6 beta4 and inhibition of ErbB2/ErbB3 signaling and hemidesmosome disassembly."xsd:string |
http://purl.uniprot.org/citations/23611113 | http://purl.uniprot.org/core/volume | "18"xsd:string |
http://purl.uniprot.org/citations/23611113 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23611113 |
http://purl.uniprot.org/citations/23611113 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23611113 |
http://purl.uniprot.org/uniprot/Q8R464#attribution-8BE93F2E4CE2580D560BE0BABB5FFE5B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23611113 |
http://purl.uniprot.org/uniprot/Q8R464#attribution-B057DF0DC26E0827D54B99A1B1E9121E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23611113 |
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http://purl.uniprot.org/uniprot/#_E2I6F8-mappedCitation-23611113 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23611113 |
http://purl.uniprot.org/uniprot/#_B4DTR1-mappedCitation-23611113 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23611113 |
http://purl.uniprot.org/uniprot/#_B4DGQ7-mappedCitation-23611113 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23611113 |
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