| http://purl.uniprot.org/citations/23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23619095 | http://www.w3.org/2000/01/rdf-schema#comment | "MicroRNAs (miRNAs) post-transcriptionally repress gene expression via the miRNA-induced silencing complex (miRISC), which includes miRNA, Argonaute and a GW182 family member. Here we show that in Caenorhabditis elegans, miRNA-mediated gene silencing is modulated by macroautophagy, a lysosome-mediated degradation process. Loss of autophagy activity suppresses developmental defects caused by partially impaired silencing of miRNA targets including the let-7 family and lsy-6. The C. elegans GW182 homolog AIN-1 is itself selectively degraded by autophagy and colocalizes with the p62 homolog SQST-1 in autophagy mutants. Thus, autophagy activity modulates miRNA-mediated gene silencing and degrades a core miRISC component."xsd:string |
| http://purl.uniprot.org/citations/23619095 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2013.53"xsd:string |
| http://purl.uniprot.org/citations/23619095 | http://purl.uniprot.org/core/author | "Zhang P."xsd:string |
| http://purl.uniprot.org/citations/23619095 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
| http://purl.uniprot.org/citations/23619095 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23619095 | http://purl.uniprot.org/core/name | "EMBO Rep"xsd:string |
| http://purl.uniprot.org/citations/23619095 | http://purl.uniprot.org/core/pages | "568-576"xsd:string |
| http://purl.uniprot.org/citations/23619095 | http://purl.uniprot.org/core/title | "Autophagy modulates miRNA-mediated gene silencing and selectively degrades AIN-1/GW182 in C. elegans."xsd:string |
| http://purl.uniprot.org/citations/23619095 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/23619095 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23619095 |
| http://purl.uniprot.org/citations/23619095 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23619095 |
| http://purl.uniprot.org/uniprot/Q17740#attribution-00DB8D9BE30E1443346271D345A75622 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23619095 |
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| http://purl.uniprot.org/uniprot/#_D5MCS2-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |
| http://purl.uniprot.org/uniprot/#_E9P873-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |
| http://purl.uniprot.org/uniprot/#_A0A2C9C2E8-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |
| http://purl.uniprot.org/uniprot/#_A0A2C9C2L0-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |
| http://purl.uniprot.org/uniprot/#_A0A2C9C358-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |
| http://purl.uniprot.org/uniprot/#_A8WHN2-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |
| http://purl.uniprot.org/uniprot/#_P34379-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |
| http://purl.uniprot.org/uniprot/#_P34443-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |
| http://purl.uniprot.org/uniprot/#_P34529-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |
| http://purl.uniprot.org/uniprot/#_F1LIM5-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |
| http://purl.uniprot.org/uniprot/#_G5EES3-mappedCitation-23619095 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23619095 |