| http://purl.uniprot.org/citations/23630347 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23630347 | http://www.w3.org/2000/01/rdf-schema#comment | "A key goal of vaccine immunotherapy is the generation of long-term memory CD8(+) T cells capable of mediating immune surveillance. We discovered a novel intercellular pathway governing the development of potent memory CD8(+) T cell responses against cell-associated Ags that is mediated through cross-presentation by XCR1(+) dendritic cells (DCs). Generation of CD8(+) memory T cells against tumor cells pulsed with an invariant NKT cell ligand depended on cross-talk between XCR1(+) and plasmacytoid DCs that was regulated by IFN-α/IFN-αR signals. IFN-α production by plasmacytoid DCs was stimulated by an OX40 signal from the invariant NKT cells, as well as an HMGB1 signal from the dying tumor cells. These findings reveal a previously unknown pathway of intercellular collaboration for the generation of tumor-specific CD8(+) memory T cells that can be exploited for strategic vaccination in the setting of tumor immunotherapy."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.1300033"xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/author | "Fujii S."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/author | "Asakura M."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/author | "Shimizu K."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/author | "Sato Y."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/author | "Hoshino K."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/author | "Kaisho T."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/author | "Ezaki T."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/author | "Shinga J."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/author | "Kitahara S."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/author | "Schoenberger S.P."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/pages | "5609-5619"xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/title | "Invariant NKT cells induce plasmacytoid dendritic cell (DC) cross-talk with conventional DCs for efficient memory CD8+ T cell induction."xsd:string |
| http://purl.uniprot.org/citations/23630347 | http://purl.uniprot.org/core/volume | "190"xsd:string |
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| http://purl.uniprot.org/uniprot/#_Q9R0M1-mappedCitation-23630347 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23630347 |