| http://purl.uniprot.org/citations/23644619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23644619 | http://www.w3.org/2000/01/rdf-schema#comment | "Controlled oxygen reperfusion could protect the lung against ischemia-reperfusion injury in cardiopulmonary bypass (CPB) by downregulating high mobility group box 1 (HMGB1), a high affinity receptor of HMGB1. This study investigated the effect of controlled oxygen reperfusion on receptor for advanced glycation end products (RAGE) expression and its downstream effects on lung ischemia-reperfusion injury. Fourteen canines received CPB with 60 minutes of aortic clamping and cardioplegic arrest followed by 90 minutes of reperfusion. Animals were randomized to receive 80% FiO2 during the entire procedure (control group) or to a test group receiving a controlled oxygen reperfusion protocol. Pathologic changes in lung tissues, RAGE expression, serum interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) were evaluated. The lung pathologic scores after 25 and 90 minutes of reperfusion were significantly lower in the test group compared with the control group (p < 0.001). RAGE expression, TNF-α, and IL-6 were downregulated by controlled oxygen treatment (p < 0.001). RAGE might be involved in the lung ischemia-reperfusion injury in canine model of CPB, which was downregulated by controlled oxygen reperfusion."xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.org/dc/terms/identifier | "doi:10.1097/mat.0b013e318290504e"xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/author | "Liu H."xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/author | "Zhang J.X."xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/author | "Ye S."xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/author | "Chen G.X."xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/author | "Rong J."xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/author | "Liang M.Y."xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/author | "Wu Z.K."xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/name | "ASAIO J"xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/pages | "302-308"xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/title | "Receptor for advanced glycation end products involved in lung ischemia reperfusion injury in cardiopulmonary bypass attenuated by controlled oxygen reperfusion in a canine model."xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://purl.uniprot.org/core/volume | "59"xsd:string |
| http://purl.uniprot.org/citations/23644619 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23644619 |
| http://purl.uniprot.org/citations/23644619 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23644619 |
| http://purl.uniprot.org/uniprot/#_C0IP02-mappedCitation-23644619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23644619 |
| http://purl.uniprot.org/uniprot/#_C0IP03-mappedCitation-23644619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23644619 |
| http://purl.uniprot.org/uniprot/#_C0IP04-mappedCitation-23644619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23644619 |
| http://purl.uniprot.org/uniprot/#_C0IP05-mappedCitation-23644619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23644619 |
| http://purl.uniprot.org/uniprot/#_C0IP06-mappedCitation-23644619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23644619 |
| http://purl.uniprot.org/uniprot/#_C0IP07-mappedCitation-23644619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23644619 |
| http://purl.uniprot.org/uniprot/#_C0IP11-mappedCitation-23644619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23644619 |
| http://purl.uniprot.org/uniprot/#_C0IP12-mappedCitation-23644619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23644619 |