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http://purl.uniprot.org/citations/2365085http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2365085http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2365085http://www.w3.org/2000/01/rdf-schema#comment"We report the isolation and characterization of the human gene encoding islet amyloid polypeptide (IAPP). Previously characterized cDNA sequences correspond to three exons of which the first is noncoding. A functional promoter region was identified in the 5' flanking DNA; however, this was farther upstream than expected. Northern blot analysis of human insulinoma RNA revealed three IAPP mRNAs of sizes 1.2, 1.8 and 2.1 kb, in agreement with three polyadenylation signals present in the 3' end of the gene. In situ hybridization to metaphase chromosomes resulted in two distinct peaks on chromosome 12, at 12p12-p13 and 12q13-q14. Southern blot analysis of genomic DNA suggested a single IAPP locus but also indicated the presence of additional homologous sequences in human genomic DNA."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.org/dc/terms/identifier"doi:10.1016/0014-5793(90)80314-9"xsd:string
http://purl.uniprot.org/citations/2365085http://purl.org/dc/terms/identifier"doi:10.1016/0014-5793(90)80314-9"xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/author"Betsholtz C."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/author"Betsholtz C."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/author"Rorsman F."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/author"Rorsman F."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/author"Stenman G."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/author"Stenman G."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/author"Christmanson L."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/author"Christmanson L."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/author"Westermark P."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/author"Westermark P."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/pages"160-166"xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/pages"160-166"xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/title"The human islet amyloid polypeptide (IAPP) gene. Organization, chromosomal localization and functional identification of a promoter region."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/title"The human islet amyloid polypeptide (IAPP) gene. Organization, chromosomal localization and functional identification of a promoter region."xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/volume"267"xsd:string
http://purl.uniprot.org/citations/2365085http://purl.uniprot.org/core/volume"267"xsd:string