| http://purl.uniprot.org/citations/23653213 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23653213 | http://www.w3.org/2000/01/rdf-schema#comment | "The production of protective antibody requires effective signalling of naive B cells following encounter with antigen, and the divergence of responding B lymphocytes into distinct lineages. Polarity proteins have recently been proposed as important mediators of both the initial B cell response, and potentially of asymmetric cell division. Here we show that, although polarity proteins of the Scribble complex, Scribble, Dlg1 and Lgl1, are expressed and polarized during early B cell activation, their deficiency has no effect on the in vivo outcome of immunization or challenge with influenza infection. Furthermore, we find a striking correlation in the differentiation outcome of daughters of single founder B cells in vitro. Taken together, our results indicate that B cell differentiation does not require polarity proteins of the Scribble complex, and the findings do not support a role for asymmetric cell division in B cell activation and differentiation."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncomms2796"xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Lew A.M."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Hawkins E.D."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Humbert P.O."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Kallies A."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Russell S.M."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Belz G.T."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Tarlinton D."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Hogan T."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Davies D."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Filby A."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Haynes N."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Seddon B."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Oliaro J."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Kinwell T."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Ramsbottom K.M."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/author | "Van Ham V."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/pages | "1801"xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/title | "Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity."xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://purl.uniprot.org/core/volume | "4"xsd:string |
| http://purl.uniprot.org/citations/23653213 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23653213 |