| http://purl.uniprot.org/citations/23673331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23673331 | http://www.w3.org/2000/01/rdf-schema#comment | "Assembly of SAS-6 dimers to form the centriolar cartwheel requires the ZYG-1/Plk4 kinase. Here, we show that ZYG-1 recruits SAS-6 to the mother centriole independently of its kinase activity; kinase activity is subsequently required for cartwheel assembly. We identify a direct interaction between ZYG-1 and the SAS-6 coiled coil that explains its kinase activity-independent function in SAS-6 recruitment. Perturbing this interaction, or the interaction between an adjacent segment of the SAS-6 coiled coil and SAS-5, prevented SAS-6 recruitment and cartwheel assembly. SAS-6 mutants with alanine substitutions in a previously described ZYG-1 target site or in 37 other residues, either phosphorylated by ZYG-1 in vitro or conserved in closely related nematodes, all supported cartwheel assembly. We propose that ZYG-1 binding to the SAS-6 coiled coil recruits the SAS-6-SAS-5 complex to the mother centriole, where a ZYG-1 kinase activity-dependent step, whose target is unlikely to be SAS-6, triggers cartwheel assembly."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.devcel.2013.03.011"xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/author | "Desai A."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/author | "Oegema K."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/author | "Niessen S."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/author | "Zhou H."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/author | "Chen S.H."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/author | "Wong Y.L."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/author | "Viscardi V."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/author | "Shiau A.K."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/author | "Lettman M.M."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/name | "Dev Cell"xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/pages | "284-298"xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/title | "Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly."xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://purl.uniprot.org/core/volume | "25"xsd:string |
| http://purl.uniprot.org/citations/23673331 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23673331 |
| http://purl.uniprot.org/citations/23673331 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23673331 |
| http://purl.uniprot.org/uniprot/Q9GT24#attribution-5CE50A21B69DD807E89D48B15989ABF9 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23673331 |
| http://purl.uniprot.org/uniprot/#_Q20010-mappedCitation-23673331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23673331 |
| http://purl.uniprot.org/uniprot/#_O62479-mappedCitation-23673331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23673331 |
| http://purl.uniprot.org/uniprot/#_Q9GT24-mappedCitation-23673331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23673331 |
| http://purl.uniprot.org/uniprot/O62479 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23673331 |
| http://purl.uniprot.org/uniprot/Q20010 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23673331 |