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http://purl.uniprot.org/citations/23678708http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23678708http://www.w3.org/2000/01/rdf-schema#comment"

Objective

To investigate the association between single nucleotide polymorphism (SNP) of the DZAL gene in infertile Han Chinese males with astheno-teratozoospermia.

Methods

We collected semen samples from 173 infertile Han Chinese men with astheno-teratozoospermia (case group) and 175 age-matched normal male volunteers (control group) for semen routine and morphological analyses. We obtained genomic DNA, genotyped the polymorphisms of the DAZL gene A260G and A386G via the Sequenom MassARRAY system, and compared the frequencies of the genotypes between the case and control groups.

Results

The AA nucleotide variant was found in the A260G and A386G polymorphisms of the DZAL gene in both the cases and controls, but the heterozygous AG variant in neither.

Conclusion

The A260G and A386G polymorphisms of the DAZL gene are not correlated with astheno-teratozoospermia-induced male infertility in the Han Chinese population, and therefore could not be considered as molecular markers of male infertility."xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/author"Wu X.Q."xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/author"Li J.P."xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/author"Mao X.M."xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/author"Yang X.X."xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/author"Zhang Y.H."xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/author"Yu Q.F."xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/author"Ye L.W."xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/name"Zhonghua Nan Ke Xue"xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/pages"311-314"xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/title"[DAZL gene polymorphisms and astheno-teratozoospermia]."xsd:string
http://purl.uniprot.org/citations/23678708http://purl.uniprot.org/core/volume"19"xsd:string
http://purl.uniprot.org/citations/23678708http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23678708
http://purl.uniprot.org/citations/23678708http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23678708
http://purl.uniprot.org/uniprot/#_A0A140VK77-mappedCitation-23678708http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23678708
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http://purl.uniprot.org/uniprot/#_Q92904-mappedCitation-23678708http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23678708
http://purl.uniprot.org/uniprot/A0A140VK77http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/23678708
http://purl.uniprot.org/uniprot/Q92904http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/23678708
http://purl.uniprot.org/uniprot/A0SWV8http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/23678708