http://purl.uniprot.org/citations/23685212 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23685212 | http://www.w3.org/2000/01/rdf-schema#comment | "Human APOBEC3F is an antiretroviral single-strand DNA cytosine deaminase, susceptible to degradation by the HIV-1 protein Vif. In this study the crystal structure of the HIV Vif binding, catalytically active, C-terminal domain of APOBEC3F (A3F-CTD) was determined. The A3F-CTD shares structural motifs with portions of APOBEC3G-CTD, APOBEC3C, and APOBEC2. Residues identified to be critical for Vif-dependent degradation of APOBEC3F all fit within a predominantly negatively charged contiguous region on the surface of A3F-CTD. Specific sequence motifs, previously shown to play a role in Vif susceptibility and virion encapsidation, are conserved across APOBEC3s and between APOBEC3s and HIV-1 Vif. In this structure these motifs pack against each other at intermolecular interfaces, providing potential insights both into APOBEC3 oligomerization and Vif interactions."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.str.2013.04.010"xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Anderson B.D."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Lu Y."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Matsuo H."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Albin J.S."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Bohn M.F."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Carpenter M.A."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Harris R.S."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Rathore A."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Schiffer C.A."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Shandilya S.M."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Somasundaran M."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Kouno T."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Evans L."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "McDougle R.M."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/author | "Davis A.N."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/name | "Structure"xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/pages | "1042-1050"xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/title | "Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain."xsd:string |
http://purl.uniprot.org/citations/23685212 | http://purl.uniprot.org/core/volume | "21"xsd:string |
http://purl.uniprot.org/citations/23685212 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23685212 |