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http://purl.uniprot.org/citations/23692331http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23692331http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23692331http://www.w3.org/2000/01/rdf-schema#comment"Lipoproteins of temperate phage are a broad family of membrane proteins encoded in the lysogeny module of temperate phages. Expression of the ltp(TP-J34) gene of temperate Streptococcus thermophilus phage TP-J34 interferes with phage infection at the stage of triggering DNA release and injection into the cell. Here, we report the first structure of a superinfection exclusion protein. We have expressed and determined the X-ray structure of Ltp(TP-J34). The soluble domain of Ltp(TP-J34) is composed of a tandem of three-helix helix-turn-helix (HTH) domains exhibiting a highly negatively charged surface. By isolating mutants of lactococcal phage P008wt with reduced sensitivities to Ltp(TP-J34) and by genome sequencing of such mutants we obtained evidence supporting the notion that Ltp(TP-J34) targets the phage's tape measure protein (TMP) and blocks its insertion into the cytoplasmic membrane."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.org/dc/terms/identifier"doi:10.1111/mmi.12267"xsd:string
http://purl.uniprot.org/citations/23692331http://purl.org/dc/terms/identifier"doi:10.1111/mmi.12267"xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Cambillau C."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Cambillau C."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Bebeacua C."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Bebeacua C."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Blangy S."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Blangy S."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Spinelli S."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Spinelli S."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Heller K.J."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Heller K.J."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Neve H."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Neve H."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Bollmann S."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Bollmann S."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Lorenzo Fajardo J.C."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/author"Lorenzo Fajardo J.C."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/name"Mol. Microbiol."xsd:string
http://purl.uniprot.org/citations/23692331http://purl.uniprot.org/core/name"Mol Microbiol"xsd:string