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http://purl.uniprot.org/citations/23711367http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23711367http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23711367http://www.w3.org/2000/01/rdf-schema#comment"Innate immune responses induced by the pattern-recognition receptors Nod1 and Nod2 play pivotal roles to combat infection and to instruct adaptive immunity. Here we identify Ankrd17 as a novel binding partner of Nod2 and show that its N-terminal domain mediates Nod2 binding. Knock-down and overexpression analysis revealed that Ankrd17 is functionally involved in Nod2- and Nod1-mediated responses in human myeloid and epithelial cells. In HeLa cells Ankrd17 contributed to pro-inflammatory responses induced by Shigella flexneri, however not to type I interferon responses induced by Sendai virus. In conclusion, this reveals a novel function for Ankrd17 in anti-bacterial innate immune pathways."xsd:string
http://purl.uniprot.org/citations/23711367http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2013.05.037"xsd:string
http://purl.uniprot.org/citations/23711367http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2013.05.037"xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/author"Kufer T.A."xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/author"Kufer T.A."xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/author"Menning M."xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/author"Menning M."xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/pages"2137-2142"xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/pages"2137-2142"xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/title"A role for the Ankyrin repeat containing protein Ankrd17 in Nod1- and Nod2-mediated inflammatory responses."xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/title"A role for the Ankyrin repeat containing protein Ankrd17 in Nod1- and Nod2-mediated inflammatory responses."xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/volume"587"xsd:string
http://purl.uniprot.org/citations/23711367http://purl.uniprot.org/core/volume"587"xsd:string
http://purl.uniprot.org/citations/23711367http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23711367
http://purl.uniprot.org/citations/23711367http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23711367
http://purl.uniprot.org/citations/23711367http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23711367
http://purl.uniprot.org/citations/23711367http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23711367
http://purl.uniprot.org/uniprot/P25205http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/23711367
http://purl.uniprot.org/uniprot/O75179http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/23711367