| http://purl.uniprot.org/citations/23731212 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23731212 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23731212 | http://www.w3.org/2000/01/rdf-schema#comment | "Besides being a public health problem, scorpion venoms have a potential biotechnological application since they contain peptides that may be used as drug leads and/or to reveal novel pharmacological targets. A comprehensive Tityus serrulatus venom proteome study with emphasis on the phosphoproteome and N-glycoproteome was performed to improve our knowledge on the molecular diversity of the proteinaceous toxins. We combined two peptide identification methodologies, i.e., database search and de novo sequencing, to achieve a more comprehensive overview of the molecular diversity of the venoms. A total of 147 proteins were identified, including neurotoxins, enzymes, bradykinin-potentiating peptides, and molecules with antimicrobial and diuretic activities. Among those, three proteins were found to be phosphorylated, and one N-glycosylated. Finally, cleavage of toxin polypeptide chains seems to be a common post-translational modification in the venom since 80% of the identified molecules were, in fact, products of toxins proteolysis."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.org/dc/terms/identifier | "doi:10.1021/pr4003068"xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.org/dc/terms/identifier | "doi:10.1021/pr4003068"xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Roepstorff P."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Roepstorff P."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Pimenta A.M."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Pimenta A.M."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Kjeldsen F."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Kjeldsen F."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Leon I.R."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Leon I.R."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Verano-Braga T."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Verano-Braga T."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Dutra A.A."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Dutra A.A."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Melo-Braga M.N."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/author | "Melo-Braga M.N."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/name | "J. Proteome Res."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/name | "J. Proteome Res."xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/pages | "3460-3470"xsd:string |
| http://purl.uniprot.org/citations/23731212 | http://purl.uniprot.org/core/pages | "3460-3470"xsd:string |