| http://purl.uniprot.org/citations/23743200 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23743200 | http://www.w3.org/2000/01/rdf-schema#comment | "DJ-1, a product of the DJ-1/PARK7 gene, has been suggested to play various functions involved in transcriptional regulation, protease activity, anti-oxidative stress activity, and regulation of mitochondrial complex I. Such a variety of functions of DJ-1 are supposed to be realized through interactions with different partner proteins. Among the candidates for DJ-1-partner proteins detected in TOF-MAS analyses of the cellular proteins co-immunoprecipitated with DJ-1, we focused here pyrroline-5-carboxylate reductase 1, PYCR1, a final key enzyme for proline biosynthesis. DJ-1 directly bound to PYCR1 in vivo and in vitro. DJ-1 and PYCR1 colocalized in mitochondria, and both were suggested to be involved in regulation of mitochondrial membrane potential, but differently. DJ-1 enhanced the enzymatic activity of PYCR1 in vitro. The cells knocked down for DJ-1 and PYCR1 showed lower viability under oxidative stress conditions. No additive nor synergistic results were obtained for the cells that had been knocked down for both DJ-1 and PYCR1, suggesting that DJ-1 and PYCR1 are on the same pathway of anti-oxidative stress protection of the cells."xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2013.05.095"xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/author | "Yasuda T."xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/author | "Shuto S."xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/author | "Arisawa M."xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/author | "Ariga H."xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/author | "Niki T."xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/author | "Iguchi-Ariga S.M."xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/author | "Kaji Y."xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/author | "Agatsuma T."xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/pages | "289-294"xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/title | "DJ-1 cooperates with PYCR1 in cell protection against oxidative stress."xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://purl.uniprot.org/core/volume | "436"xsd:string |
| http://purl.uniprot.org/citations/23743200 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23743200 |
| http://purl.uniprot.org/citations/23743200 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23743200 |
| http://purl.uniprot.org/uniprot/P32322#attribution-C3DE712326D803DC49E6173C538D8D19 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23743200 |
| http://purl.uniprot.org/uniprot/Q99497#attribution-7A3002C35C3663570817B49E2B086740 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23743200 |
| http://purl.uniprot.org/uniprot/Q99497#attribution-7D912AC280F372A536796102F060E7AF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23743200 |
| http://purl.uniprot.org/uniprot/Q99497#attribution-C3DE712326D803DC49E6173C538D8D19 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23743200 |
| http://purl.uniprot.org/uniprot/O43272#attribution-7A3002C35C3663570817B49E2B086740 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23743200 |
| http://purl.uniprot.org/uniprot/#_D3K2X3-mappedCitation-23743200 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23743200 |
| http://purl.uniprot.org/uniprot/#_A2A813-mappedCitation-23743200 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23743200 |