http://purl.uniprot.org/citations/23749191 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23749191 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23749191 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23749191 | http://www.w3.org/2000/01/rdf-schema#comment | "The duck (Anas platyrhynchos) is one of the principal natural hosts of influenza A viruses. We present the duck genome sequence and perform deep transcriptome analyses to investigate immune-related genes. Our data indicate that the duck possesses a contractive immune gene repertoire, as in chicken and zebra finch, and this repertoire has been shaped through lineage-specific duplications. We identify genes that are responsive to influenza A viruses using the lung transcriptomes of control ducks and ones that were infected with either a highly pathogenic (A/duck/Hubei/49/05) or a weakly pathogenic (A/goose/Hubei/65/05) H5N1 virus. Further, we show how the duck's defense mechanisms against influenza infection have been optimized through the diversification of its β-defensin and butyrophilin-like repertoires. These analyses, in combination with the genomic and transcriptomic data, provide a resource for characterizing the interaction between host and influenza viruses."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng.2657"xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng.2657"xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng.2657"xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Du Z."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Du Z."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Du Z."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Chen H."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Chen H."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Chen H."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Cai Q."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Cai Q."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Cai Q."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Feng H."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Feng H."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Feng H."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Huang Y."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Huang Y."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Huang Y."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Hu X."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Hu X."xsd:string |
http://purl.uniprot.org/citations/23749191 | http://purl.uniprot.org/core/author | "Hu X."xsd:string |