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http://purl.uniprot.org/citations/23757853http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23757853http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23757853http://www.w3.org/2000/01/rdf-schema#comment"Since late 2010, porcine epidemic diarrhea virus (PEDV) has been re-emerging in central China. To explore the possible reason of the PEDV outbreaks, twelve PEDV field strains were isolated from different swine breeding farms in central China during 2010-2012, and molecular diversity, phylogenetic relationships of these strains with other PEDV reference strains were investigated. Sequence analysis of S, M and ORE3 genes revealed that the central China PEDV isolates had several specific nucleotides and amino acids which were different from PEDV reference strains. In addition, the entire S genes of eleven central China PEDV isolates were found to be nine nucleotides longer in length than CV777 and large number of amino acid variations was accumulated in the N-terminal region of S gene. Phylogenetic analysis showed that the central China PEDV isolates had close relationship with Korea strains (2007-2009), Thailand strains (2007-2008), Vietnam strains (2009-2010), Japan strains (2010), and other prevailing strains from other parts of China (2010-2012). However, they differed genetically from European strains (CV777, Brl/87), China strains (2003-2007) and the vaccine strains (CV777) used in China. These results imply that a rapid variation and evolution of central China PEDV strains has occurred in recent years, and a more efficient vaccine strain should be selected to prevent and control outbreaks of PEDV in China."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Chen L."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Chen L."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Zhao J."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Zhao J."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Wang X.M."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Wang X.M."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Wang C.Q."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Wang C.Q."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Chang H.T."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Chang H.T."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Huo J.Y."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Huo J.Y."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Zheng F.M."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/author"Zheng F.M."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/name"Ping Tu Hsueh Pao"xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/name"Bing Du Xue Bao"xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/pages"197-205"xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/pages"197-205"xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/title"Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus field strains in central China during 2010-2012 outbreaks."xsd:string
http://purl.uniprot.org/citations/23757853http://purl.uniprot.org/core/title"[Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus field strains in central China during 2010-2012 outbreaks]."xsd:string