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http://purl.uniprot.org/citations/23765972 | http://www.w3.org/2000/01/rdf-schema#comment | "We made a case-control study to investigate a possible association between ALOX5AP-SG13S114A/T, COX-2-765G/C, and COX-1-50C/T polymorphisms with cerebral infarction in a Chinese population. A total of 411 cases with cerebral infarction were included; 411 controls matched for age, gender, and risk factors were also selected. The ALOX5AP-SG13S114A/T (rs10507391), COX-2-765G/C (rs20417), and COX-1-50C/T (rs3842787) polymorphisms were determined using PCR-RFLP. The generalized multifactor dimensionality reduction method was employed to detect gene-gene interactions. Based on single-gene analysis, there were no significant differences in the genotype and allele frequency distributions of ALOX5AP-SG13S114A/T, COX-2-765G/C, and COX-1-50C/T between the cerebral infarction group and controls. However, in those cases carrying ALOX5AP-SG13S114AA as well as COX-2-765CC, the risk of cerebral infarction increased significantly by 2.84 times (95%CI = 1.324-6.543). The single-gene ALOX5AP-SG13S114A/T, COX-2-765G/C, and COX-1-50C/T polymorphisms appear not to be associated with the development of cerebral infarction in Chinese populations. However, the interaction between ALOX5AP-SG13S114AA and COX-2-765CC apparently increases susceptibility to cerebral infarction."xsd:string |
http://purl.uniprot.org/citations/23765972 | http://purl.org/dc/terms/identifier | "doi:10.4238/2013.may.14.6"xsd:string |
http://purl.uniprot.org/citations/23765972 | http://purl.uniprot.org/core/author | "Lin J."xsd:string |
http://purl.uniprot.org/citations/23765972 | http://purl.uniprot.org/core/author | "Zhou Q."xsd:string |
http://purl.uniprot.org/citations/23765972 | http://purl.uniprot.org/core/author | "Yi X.Y."xsd:string |
http://purl.uniprot.org/citations/23765972 | http://purl.uniprot.org/core/author | "Chi L.F."xsd:string |
http://purl.uniprot.org/citations/23765972 | http://purl.uniprot.org/core/author | "Chi W.Z."xsd:string |
http://purl.uniprot.org/citations/23765972 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23765972 | http://purl.uniprot.org/core/name | "Genet Mol Res"xsd:string |
http://purl.uniprot.org/citations/23765972 | http://purl.uniprot.org/core/pages | "1660-1669"xsd:string |
http://purl.uniprot.org/citations/23765972 | http://purl.uniprot.org/core/title | "Interaction between ALOX5AP-SG13S114A/T and COX-2-765G/C increases susceptibility to cerebral infarction in a Chinese population."xsd:string |
http://purl.uniprot.org/citations/23765972 | http://purl.uniprot.org/core/volume | "12"xsd:string |
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