| http://purl.uniprot.org/citations/23810393 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23810393 | http://www.w3.org/2000/01/rdf-schema#comment | "Tuberin is a negative regulator of mTOR pathway. To investigate the function of tuberin during liver regeneration, we performed 70% hepatectomy on wild-type and Tsc2+/-mice. We found the tuberin phosphorylation correlated with mTOR activation during early liver regeneration in wild-type mice. However, liver regeneration in the Tsc2+/- mice was not enhanced. Instead, the Tsc2+/-livers failed to accumulate lipid bodies, and this was accompanied by increased mortality. These findings suggest that tuberin plays a critical role in liver energy balance by regulating hepatocellular lipid accumulation during early liver regeneration. These effects may influence the role of mTORC1 on cell growth and proliferation."xsd:string |
| http://purl.uniprot.org/citations/23810393 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2013.06.056"xsd:string |
| http://purl.uniprot.org/citations/23810393 | http://purl.uniprot.org/core/author | "Yeung R.S."xsd:string |
| http://purl.uniprot.org/citations/23810393 | http://purl.uniprot.org/core/author | "Fausto N."xsd:string |
| http://purl.uniprot.org/citations/23810393 | http://purl.uniprot.org/core/author | "Campbell J.S."xsd:string |
| http://purl.uniprot.org/citations/23810393 | http://purl.uniprot.org/core/author | "Obayashi Y."xsd:string |
| http://purl.uniprot.org/citations/23810393 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23810393 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/23810393 | http://purl.uniprot.org/core/pages | "146-150"xsd:string |
| http://purl.uniprot.org/citations/23810393 | http://purl.uniprot.org/core/title | "Impaired lipid accumulation in the liver of Tsc2-heterozygous mice during liver regeneration."xsd:string |
| http://purl.uniprot.org/citations/23810393 | http://purl.uniprot.org/core/volume | "437"xsd:string |
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