http://purl.uniprot.org/citations/23812587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23812587 | http://www.w3.org/2000/01/rdf-schema#comment | "During normal translation, the binding of a release factor to one of the three stop codons (UGA, UAA or UAG) results in the termination of protein synthesis. However, modification of the initial uridine to a pseudouridine (Ψ) allows efficient recognition and read-through of these stop codons by a transfer RNA (tRNA), although it requires the formation of two normally forbidden purine-purine base pairs. Here we determined the crystal structure at 3.1 Å resolution of the 30S ribosomal subunit in complex with the anticodon stem loop of tRNA(Ser) bound to the ΨAG stop codon in the A site. The ΨA base pair at the first position is accompanied by the formation of purine-purine base pairs at the second and third positions of the codon, which show an unusual Watson-Crick/Hoogsteen geometry. The structure shows a previously unsuspected ability of the ribosomal decoding centre to accommodate non-canonical base pairs."xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature12302"xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/author | "Wu G."xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/author | "Ramakrishnan V."xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/author | "Fernandez I.S."xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/author | "Ng C.L."xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/author | "Kelley A.C."xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/author | "Yu Y.T."xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/pages | "107-110"xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/title | "Unusual base pairing during the decoding of a stop codon by the ribosome."xsd:string |
http://purl.uniprot.org/citations/23812587 | http://purl.uniprot.org/core/volume | "500"xsd:string |
http://purl.uniprot.org/citations/23812587 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23812587 |
http://purl.uniprot.org/citations/23812587 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23812587 |
http://purl.uniprot.org/uniprot/#_P35871-mappedCitation-23812587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23812587 |
http://purl.uniprot.org/uniprot/#_P0DOY6-mappedCitation-23812587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23812587 |
http://purl.uniprot.org/uniprot/#_P0DOY7-mappedCitation-23812587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23812587 |
http://purl.uniprot.org/uniprot/#_P0DOY8-mappedCitation-23812587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23812587 |
http://purl.uniprot.org/uniprot/#_P0DOY9-mappedCitation-23812587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23812587 |
http://purl.uniprot.org/uniprot/#_P17291-mappedCitation-23812587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23812587 |
http://purl.uniprot.org/uniprot/#_P80339-mappedCitation-23812587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23812587 |
http://purl.uniprot.org/uniprot/#_P80340-mappedCitation-23812587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23812587 |
http://purl.uniprot.org/uniprot/#_P80371-mappedCitation-23812587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23812587 |