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http://purl.uniprot.org/citations/23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23821035http://www.w3.org/2000/01/rdf-schema#comment"The control of organ growth is a fundamental aspect of animal development but remains poorly understood. The morphogen Dpp has long been considered as a general promoter of cell proliferation during Drosophila wing development. It is an ongoing debate whether the Dpp gradient is required for the uniform cell proliferation observed in the wing imaginal disc. Here, we investigated how the Dpp signaling pathway regulates proliferation during wing development. By systematic manipulation of Dpp signaling we observed that it controls proliferation in a region-specific manner: Dpp, via omb, promoted proliferation in the lateral and repressed proliferation in the medial wing disc. Omb controlled the regional proliferation rate by oppositely regulating transcription of the microRNA gene bantam in medial versus lateral wing disc. However, neither the Dpp nor Omb gradient was essential for uniform proliferation along the anteroposterior axis."xsd:string
http://purl.uniprot.org/citations/23821035http://purl.org/dc/terms/identifier"doi:10.1242/dev.094300"xsd:string
http://purl.uniprot.org/citations/23821035http://purl.uniprot.org/core/author"Luo D."xsd:string
http://purl.uniprot.org/citations/23821035http://purl.uniprot.org/core/author"Shen J."xsd:string
http://purl.uniprot.org/citations/23821035http://purl.uniprot.org/core/author"Zhang X."xsd:string
http://purl.uniprot.org/citations/23821035http://purl.uniprot.org/core/author"Pflugfelder G.O."xsd:string
http://purl.uniprot.org/citations/23821035http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23821035http://purl.uniprot.org/core/name"Development"xsd:string
http://purl.uniprot.org/citations/23821035http://purl.uniprot.org/core/pages"2917-2922"xsd:string
http://purl.uniprot.org/citations/23821035http://purl.uniprot.org/core/title"Dpp signaling inhibits proliferation in the Drosophila wing by Omb-dependent regional control of bantam."xsd:string
http://purl.uniprot.org/citations/23821035http://purl.uniprot.org/core/volume"140"xsd:string
http://purl.uniprot.org/citations/23821035http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23821035
http://purl.uniprot.org/citations/23821035http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23821035
http://purl.uniprot.org/uniprot/#_E1JHD6-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035
http://purl.uniprot.org/uniprot/#_A0A6H2EEY2-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035
http://purl.uniprot.org/uniprot/#_E1JJD8-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035
http://purl.uniprot.org/uniprot/#_M9NE80-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035
http://purl.uniprot.org/uniprot/#_M9NEV8-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035
http://purl.uniprot.org/uniprot/#_P07713-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035
http://purl.uniprot.org/uniprot/#_Q24432-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035
http://purl.uniprot.org/uniprot/#_Q27933-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035
http://purl.uniprot.org/uniprot/#_M9PH16-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035
http://purl.uniprot.org/uniprot/#_O15968-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035
http://purl.uniprot.org/uniprot/#_Q24326-mappedCitation-23821035http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23821035