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http://purl.uniprot.org/citations/2383398 | http://www.w3.org/2000/01/rdf-schema#comment | "We used transient transfection in COS cells to compare the properties of mouse muscle acetylcholine receptors (AChRs) containing alpha, beta, delta, and either gamma or epsilon subunits. gamma- and epsilon-AChRs had identical association rates for binding 125I-alpha-bungarotoxin, and identical curves for inhibition of toxin binding by d-tubocurarine, but epsilon-AChRs had a significantly longer half-time of turnover in the membrane than gamma-AChRs. A myasthenic serum specific for the embryonic form of the AChR reduced toxin binding to gamma-, but not epsilon-AChRs. The gamma-AChRs had channel characteristics of embryonic AChRs, whereas the major class of epsilon-AChR channels had the characteristics of adult AChRs. Two minor channel classes with smaller conductances were also seen with epsilon-AChR. Thus, some, but not all, of the differences between AChRs at adult endplates and those in the extrasynaptic membrane can be explained by the difference in subunit composition of gamma- and epsilon-AChRs."xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.org/dc/terms/identifier | "doi:10.1016/0896-6273(90)90305-y"xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/author | "Gu Y."xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/author | "Gardner P.D."xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/author | "Forsayeth J.R."xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/author | "Franco A. Jr."xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/author | "Lansman J.B."xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/author | "Hall Z.W."xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/pages | "147-157"xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/title | "Properties of embryonic and adult muscle acetylcholine receptors transiently expressed in COS cells."xsd:string |
http://purl.uniprot.org/citations/2383398 | http://purl.uniprot.org/core/volume | "5"xsd:string |
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