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http://purl.uniprot.org/citations/23834814 | http://www.w3.org/2000/01/rdf-schema#comment | "The prevention of oral squamous cell carcinoma metastasis to improve overall patient survival has provided the rationale for biomarker development. We used the Transwell invasion assay to isolate a highly metastatic subpopulation, HSC-3-5 cells, with almost the same genetic background as HSC-3 cells but a higher metastatic capacity accompanied by cytoskeletal rearrangements and mesenchymal transformation. HSC-3-5 cells also showed tumorigenic and metastatic characteristics in vivo. In addition, Anterior gradient 2 (agr2), a pro-oncogenic signaling intermediate, was identified from gene expression profiling, and overexpression of AGR2 showed a positive correlation with oral tumor metastasis. Taken together, our data suggest that AGR2 may be a novel sensitive biomarker for metastatic oral cancer."xsd:string |
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http://purl.uniprot.org/citations/23834814 | http://purl.uniprot.org/core/author | "Chen Y.L."xsd:string |
http://purl.uniprot.org/citations/23834814 | http://purl.uniprot.org/core/author | "Ho C.L."xsd:string |
http://purl.uniprot.org/citations/23834814 | http://purl.uniprot.org/core/author | "Chang C.F."xsd:string |
http://purl.uniprot.org/citations/23834814 | http://purl.uniprot.org/core/author | "Chen Y.T."xsd:string |
http://purl.uniprot.org/citations/23834814 | http://purl.uniprot.org/core/author | "Chen P.K."xsd:string |
http://purl.uniprot.org/citations/23834814 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23834814 | http://purl.uniprot.org/core/name | "Cancer Lett"xsd:string |
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http://purl.uniprot.org/citations/23834814 | http://purl.uniprot.org/core/title | "Anterior gradient 2: a novel sensitive tumor marker for metastatic oral cancer."xsd:string |
http://purl.uniprot.org/citations/23834814 | http://purl.uniprot.org/core/volume | "339"xsd:string |
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