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http://purl.uniprot.org/citations/23834814http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23834814http://www.w3.org/2000/01/rdf-schema#comment"The prevention of oral squamous cell carcinoma metastasis to improve overall patient survival has provided the rationale for biomarker development. We used the Transwell invasion assay to isolate a highly metastatic subpopulation, HSC-3-5 cells, with almost the same genetic background as HSC-3 cells but a higher metastatic capacity accompanied by cytoskeletal rearrangements and mesenchymal transformation. HSC-3-5 cells also showed tumorigenic and metastatic characteristics in vivo. In addition, Anterior gradient 2 (agr2), a pro-oncogenic signaling intermediate, was identified from gene expression profiling, and overexpression of AGR2 showed a positive correlation with oral tumor metastasis. Taken together, our data suggest that AGR2 may be a novel sensitive biomarker for metastatic oral cancer."xsd:string
http://purl.uniprot.org/citations/23834814http://purl.org/dc/terms/identifier"doi:10.1016/j.canlet.2013.06.025"xsd:string
http://purl.uniprot.org/citations/23834814http://purl.uniprot.org/core/author"Chen Y.L."xsd:string
http://purl.uniprot.org/citations/23834814http://purl.uniprot.org/core/author"Ho C.L."xsd:string
http://purl.uniprot.org/citations/23834814http://purl.uniprot.org/core/author"Chang C.F."xsd:string
http://purl.uniprot.org/citations/23834814http://purl.uniprot.org/core/author"Chen Y.T."xsd:string
http://purl.uniprot.org/citations/23834814http://purl.uniprot.org/core/author"Chen P.K."xsd:string
http://purl.uniprot.org/citations/23834814http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23834814http://purl.uniprot.org/core/name"Cancer Lett"xsd:string
http://purl.uniprot.org/citations/23834814http://purl.uniprot.org/core/pages"270-278"xsd:string
http://purl.uniprot.org/citations/23834814http://purl.uniprot.org/core/title"Anterior gradient 2: a novel sensitive tumor marker for metastatic oral cancer."xsd:string
http://purl.uniprot.org/citations/23834814http://purl.uniprot.org/core/volume"339"xsd:string
http://purl.uniprot.org/citations/23834814http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23834814
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