RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/23852386http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23852386http://www.w3.org/2000/01/rdf-schema#comment"The first microRNAs were discovered some 20 years ago, but only a small fraction of the microRNA-encoding genes have been described in detail yet. Here we report the molecular analysis of a computationally predicted Drosophila melanogaster microRNA gene, mir-282. We show that the mir-282 gene is the source of a 4.9-kb-long primary transcript with a 5' cap and a 3'-poly(A) sequence and a mature microRNA of ∼25 bp. Our data strongly suggest the existence of an independent mir-282 gene conserved in holometabolic insects. We give evidence that the mir-282 locus encodes a functional transcript that influences viability, longevity, and egg production in Drosophila. We identify the nervous system-specific adenylate cyclase (rutabaga) as a target of miR-282 and assume that one of the main functions of mir-282 is the regulation of adenylate cyclase activity in the nervous system during metamorphosis."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.org/dc/terms/identifier"doi:10.1534/genetics.113.153585"xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Havelda Z."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Lukacsovich T."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Varallyay E."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Vilmos P."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Erdelyi M."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Szabad J."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Jankovics F."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Kristo I."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Kucerova L."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Somogyi K."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Szuperak M."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Henn L."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/author"Bujna A."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/name"Genetics"xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/pages"469-480"xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/title"Viability, longevity, and egg production of Drosophila melanogaster are regulated by the miR-282 microRNA."xsd:string
http://purl.uniprot.org/citations/23852386http://purl.uniprot.org/core/volume"195"xsd:string
http://purl.uniprot.org/citations/23852386http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23852386
http://purl.uniprot.org/citations/23852386http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23852386
http://purl.uniprot.org/uniprot/#_A0A0B4KFW0-mappedCitation-23852386http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23852386
http://purl.uniprot.org/uniprot/#_A0A0B4K849-mappedCitation-23852386http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23852386