| http://purl.uniprot.org/citations/23861867 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23861867 | http://www.w3.org/2000/01/rdf-schema#comment | "Hepatitis C virus (HCV) is highly dependent on cellular factors for its own propagation. By employing tandem affinity purification method, we identified pyruvate carboxylase (PC) as a cellular partner for NS5A protein. NS5A interacted with PC through the N-terminal region of NS5A and the biotin carboxylase domain of PC. PC expression was decreased in cells expressing NS5A and HCV-infected cells. Promoter activity of PC was also decreased by NS5A protein. However, FAS expression was increased in cells expressing NS5A and cell culture grown HCV (HCVcc)-infected cells. Silencing of PC promoted fatty acid synthase (FAS) expression level. These data suggest HCV may modulate PC via NS5A protein for its own propagation."xsd:string |
| http://purl.uniprot.org/citations/23861867 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0068170"xsd:string |
| http://purl.uniprot.org/citations/23861867 | http://purl.uniprot.org/core/author | "Kim J.W."xsd:string |
| http://purl.uniprot.org/citations/23861867 | http://purl.uniprot.org/core/author | "Hwang S.B."xsd:string |
| http://purl.uniprot.org/citations/23861867 | http://purl.uniprot.org/core/author | "Lim Y.S."xsd:string |
| http://purl.uniprot.org/citations/23861867 | http://purl.uniprot.org/core/author | "Yim S.A."xsd:string |
| http://purl.uniprot.org/citations/23861867 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23861867 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
| http://purl.uniprot.org/citations/23861867 | http://purl.uniprot.org/core/pages | "e68170"xsd:string |
| http://purl.uniprot.org/citations/23861867 | http://purl.uniprot.org/core/title | "Nonstructural 5A protein of hepatitis C virus interacts with pyruvate carboxylase and modulates viral propagation."xsd:string |
| http://purl.uniprot.org/citations/23861867 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/23861867 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23861867 |
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| http://purl.uniprot.org/uniprot/P11498#attribution-55D10D0FE5E522CEF6A8FFFF5BDAE312 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23861867 |
| http://purl.uniprot.org/uniprot/P11498#attribution-C0AD7ACBC739F3719A4546ABA5DA9321 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23861867 |
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