| http://purl.uniprot.org/citations/23870131 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23870131 | http://www.w3.org/2000/01/rdf-schema#comment | "Mutations in whole organisms are powerful ways of interrogating gene function in a realistic context. We describe a program, the Sanger Institute Mouse Genetics Project, that provides a step toward the aim of knocking out all genes and screening each line for a broad range of traits. We found that hitherto unpublished genes were as likely to reveal phenotypes as known genes, suggesting that novel genes represent a rich resource for investigating the molecular basis of disease. We found many unexpected phenotypes detected only because we screened for them, emphasizing the value of screening all mutants for a wide range of traits. Haploinsufficiency and pleiotropy were both surprisingly common. Forty-two percent of genes were essential for viability, and these were less likely to have a paralog and more likely to contribute to a protein complex than other genes. Phenotypic data and more than 900 mutants are openly available for further analysis. PAPERCLIP:"xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cell.2013.06.022"xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Brown T."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Adams D.J."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Alexander L."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Dougan G."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Edwards A."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Clarke K."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Holroyd S."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Flint J."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Lewis M."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Li W."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Ingham N.J."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "McDermott J."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Woodward J."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "West A.P."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Steel K.P."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Vancollie V.E."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "White J.K."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Bottomley J.R."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Cook R."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Lucas M."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Bradley A."xsd:string |
| http://purl.uniprot.org/citations/23870131 | http://purl.uniprot.org/core/author | "Pearson S."xsd:string |