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http://purl.uniprot.org/citations/23874544http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23874544http://www.w3.org/2000/01/rdf-schema#comment"Metastasis remains to be one of the most prevalent causes leading to poor long-term survival of colorectal cancer (CRC) patients. The clinical significances of tumor metastatic suppressor, N-myc downregulated gene 1 (NDRG1), have been inconsistently reported in a variety of cancerous diseases. In this study with 240 CRC clinical specimens, we showed that NDRG1 expression was significantly decreased in most of CRC tissues compared to the paired non-tumor counterparts. Statistical analysis revealed a significant inverse correlation of NDRG1 expression with tumor stage, differentiation status and metastasis. Compared with NDRG1-negative group, NDRG1-positve group had better disease-free/overall survival (p = 0.000) over 5 years' follow-up. Furthermore, NDRG1 was considered to be an independent prognostic factor for overall survival (p = 0.001) and recurrence (p = 0.003). Our study concludes that NDRG1 is a novel favorable predictor for the prognosis in CRC patients."xsd:string
http://purl.uniprot.org/citations/23874544http://purl.org/dc/terms/identifier"doi:10.1371/journal.pone.0068206"xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/author"Ma J."xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/author"Dong F."xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/author"Sun J."xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/author"Zheng M."xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/author"Zhang D."xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/author"Feng B."xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/author"Mao Z."xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/author"Zang L."xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/name"PLoS One"xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/pages"e68206"xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/title"The metastasis suppressor, N-myc downregulated gene 1 (NDRG1), is a prognostic biomarker for human colorectal cancer."xsd:string
http://purl.uniprot.org/citations/23874544http://purl.uniprot.org/core/volume"8"xsd:string
http://purl.uniprot.org/citations/23874544http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23874544
http://purl.uniprot.org/citations/23874544http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23874544
http://purl.uniprot.org/uniprot/#_A0A6Q8PHF2-mappedCitation-23874544http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23874544
http://purl.uniprot.org/uniprot/#_B3KU62-mappedCitation-23874544http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23874544
http://purl.uniprot.org/uniprot/#_B7Z4H0-mappedCitation-23874544http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23874544
http://purl.uniprot.org/uniprot/#_B7Z505-mappedCitation-23874544http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23874544
http://purl.uniprot.org/uniprot/#_B3KWB2-mappedCitation-23874544http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23874544
http://purl.uniprot.org/uniprot/#_B7Z5Z7-mappedCitation-23874544http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23874544
http://purl.uniprot.org/uniprot/#_Q53EU7-mappedCitation-23874544http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23874544