| http://purl.uniprot.org/citations/23902156 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23902156 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23902156 | http://www.w3.org/2000/01/rdf-schema#comment | "A ribosomal P1 protein, Pen b 26 from Penicillium brevicompactum, was previously identified as a major allergen. A homolog protein was isolated and characterized from Penicillium crustosum which is not known to be allergenic mold. A cDNA library of P. crustosum was constructed and screened using a probe based on the DNA sequence of Pen b 26. A positive clone was isolated, expressed in Escherichia coli, purified and characterized by comparing its immunological and physical properties to Pen b 26. It was designated as Pen cr 26 and had a 321 nt ORF corresponding to 107 amino acids with a MW of 11 kDa. Pen cr 26 had strong sequence homology to Pen b 26 (92% for nucleotides and 86% for amino acids) and its physical and predicted structural properties were similar to the latter. The level of expression of Pen cr 26 was much lower than that of Pen b 26 in the same expression vector. Both proteins were recognized equally well by the IgG class specific antibodies, but Pen cr 26 was poorly recognized by Penicillium-sensitive atopic sera (IgE), suggesting striking antigenic difference in IgE epitopes, i.e., 87% were positive for Pen b 26 while only 23% were positive for Pen cr 26. The allergenicity of Pen cr 26 seems to be minor in nature and it could be a hypoallergenic variant of Pen b 26."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.org/dc/terms/identifier | "doi:10.3109/13693786.2013.813086"xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.org/dc/terms/identifier | "doi:10.3109/13693786.2013.813086"xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/author | "Kumar V."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/author | "Kumar V."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/author | "Vijay H.M."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/author | "Vijay H.M."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/author | "Lemieux M."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/author | "Lemieux M."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/author | "Sevinc M.S."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/author | "Sevinc M.S."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/author | "Abebe M."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/author | "Abebe M."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/name | "Med. Mycol."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/name | "Med. Mycol."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/pages | "81-89"xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/pages | "81-89"xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/title | "Isolation, expression and characterization of a minor allergen from Penicillium crustosum."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/title | "Isolation, expression and characterization of a minor allergen from Penicillium crustosum."xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/volume | "52"xsd:string |
| http://purl.uniprot.org/citations/23902156 | http://purl.uniprot.org/core/volume | "52"xsd:string |