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http://purl.uniprot.org/citations/23907008http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23907008http://www.w3.org/2000/01/rdf-schema#comment"Rv2140c is one of many conserved Mycobacterium tuberculosis proteins for which no molecular function has been identified. We have determined a high-resolution crystal structure of the Rv2140c gene product, which reveals a dimeric complex that shares strong structural homology with the phosphatidylethanolamine-binding family of proteins. Rv2140c forms low-millimolar interactions with a selection of soluble phosphatidylethanolamine analogs, indicating that it has a role in lipid metabolism. Furthermore, the small molecule locostatin binds to the Rv2140c ligand-binding site and also inhibits the growth of the model organism Mycobacterium smegmatis."xsd:string
http://purl.uniprot.org/citations/23907008http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2013.07.038"xsd:string
http://purl.uniprot.org/citations/23907008http://purl.uniprot.org/core/author"Wilmanns M."xsd:string
http://purl.uniprot.org/citations/23907008http://purl.uniprot.org/core/author"Holton S.J."xsd:string
http://purl.uniprot.org/citations/23907008http://purl.uniprot.org/core/author"Diehl A."xsd:string
http://purl.uniprot.org/citations/23907008http://purl.uniprot.org/core/author"Higman V.A."xsd:string
http://purl.uniprot.org/citations/23907008http://purl.uniprot.org/core/author"Eulenburg G."xsd:string
http://purl.uniprot.org/citations/23907008http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23907008http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/23907008http://purl.uniprot.org/core/pages"2936-2942"xsd:string
http://purl.uniprot.org/citations/23907008http://purl.uniprot.org/core/title"Structural and biochemical characterization of Rv2140c, a phosphatidylethanolamine-binding protein from Mycobacterium tuberculosis."xsd:string
http://purl.uniprot.org/citations/23907008http://purl.uniprot.org/core/volume"587"xsd:string
http://purl.uniprot.org/citations/23907008http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23907008
http://purl.uniprot.org/citations/23907008http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23907008
http://purl.uniprot.org/uniprot/P9WFN1#attribution-C4D1BF03AACDF66FAE174271BC23E5F6http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/23907008
http://purl.uniprot.org/uniprot/#_P9WFN1-mappedCitation-23907008http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23907008
http://purl.uniprot.org/uniprot/P9WFN1http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/23907008