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http://purl.uniprot.org/citations/23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23912278http://www.w3.org/2000/01/rdf-schema#comment"In protein synthesis, elongation factor G (EF-G) facilitates movement of tRNA-mRNA by one codon, which is coupled to the ratchet-like rotation of the ribosome complex and is triggered by EF-G-mediated GTP hydrolysis. Here we report the structure of a pretranslocational ribosome bound to Thermus thermophilus EF-G trapped with a GTP analog. The positioning of the catalytic His87 into the active site coupled to hydrophobic-gate opening involves the 23S rRNA sarcin-ricin loop and domain III of EF-G and provides a structural basis for the GTPase activation of EF-G. Interactions of the hybrid peptidyl-site-exit-site tRNA with ribosomal elements, including the entire L1 stalk and proteins S13 and S19, shed light on how formation and stabilization of the hybrid tRNA is coupled to head swiveling and body rotation of the 30S as well as to closure of the L1 stalk."xsd:string
http://purl.uniprot.org/citations/23912278http://purl.org/dc/terms/identifier"doi:10.1038/nsmb.2645"xsd:string
http://purl.uniprot.org/citations/23912278http://purl.uniprot.org/core/author"Chen Y."xsd:string
http://purl.uniprot.org/citations/23912278http://purl.uniprot.org/core/author"Feng S."xsd:string
http://purl.uniprot.org/citations/23912278http://purl.uniprot.org/core/author"Gao Y.G."xsd:string
http://purl.uniprot.org/citations/23912278http://purl.uniprot.org/core/author"Kumar V."xsd:string
http://purl.uniprot.org/citations/23912278http://purl.uniprot.org/core/author"Ero R."xsd:string
http://purl.uniprot.org/citations/23912278http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23912278http://purl.uniprot.org/core/name"Nat Struct Mol Biol"xsd:string
http://purl.uniprot.org/citations/23912278http://purl.uniprot.org/core/pages"1077-1084"xsd:string
http://purl.uniprot.org/citations/23912278http://purl.uniprot.org/core/title"Structure of EF-G-ribosome complex in a pretranslocation state."xsd:string
http://purl.uniprot.org/citations/23912278http://purl.uniprot.org/core/volume"20"xsd:string
http://purl.uniprot.org/citations/23912278http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23912278
http://purl.uniprot.org/citations/23912278http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23912278
http://purl.uniprot.org/uniprot/#_P35871-mappedCitation-23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23912278
http://purl.uniprot.org/uniprot/#_P0DOY6-mappedCitation-23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23912278
http://purl.uniprot.org/uniprot/#_P0DOY7-mappedCitation-23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23912278
http://purl.uniprot.org/uniprot/#_P0DOY8-mappedCitation-23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23912278
http://purl.uniprot.org/uniprot/#_P0DOY9-mappedCitation-23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23912278
http://purl.uniprot.org/uniprot/#_P17291-mappedCitation-23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23912278
http://purl.uniprot.org/uniprot/#_P80339-mappedCitation-23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23912278
http://purl.uniprot.org/uniprot/#_P80340-mappedCitation-23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23912278
http://purl.uniprot.org/uniprot/#_P80371-mappedCitation-23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23912278
http://purl.uniprot.org/uniprot/#_P80372-mappedCitation-23912278http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23912278