http://purl.uniprot.org/citations/23935104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23935104 | http://www.w3.org/2000/01/rdf-schema#comment | "Cytokine responsiveness is a critical component of the ability of cells to respond to the extracellular milieu. Transcription factor-mediated regulation of cytokine receptor expression is a common mode of altering responses to the external environment. We identify the transcription factor Twist1 as a component of a STAT3-induced feedback loop that controls IL-6 signals by directly repressing Il6ra. Human and mouse T cells lacking Twist1 have an increased ability to differentiate into Th17 cells. Mice with a T cell-specific deletion of Twist1 demonstrate increased Th17 and T follicular helper cell development, early onset experimental autoimmune encephalomyelitis, and increased antigen-specific antibody responses. Thus, Twist1 has a critical role in limiting both cell-mediated and humoral immunity."xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m113.497248"xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/author | "Blum J.S."xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/author | "Kaplan M.H."xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/author | "Pham D."xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/author | "Firulli A.B."xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/author | "Dent A.L."xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/author | "Hollister K."xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/author | "Walline C.C."xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/pages | "27423-27433"xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/title | "The transcription factor Twist1 limits T helper 17 and T follicular helper cell development by repressing the gene encoding the interleukin-6 receptor alpha chain."xsd:string |
http://purl.uniprot.org/citations/23935104 | http://purl.uniprot.org/core/volume | "288"xsd:string |
http://purl.uniprot.org/citations/23935104 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23935104 |
http://purl.uniprot.org/citations/23935104 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23935104 |
http://purl.uniprot.org/uniprot/#_A0A087WTB5-mappedCitation-23935104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23935104 |
http://purl.uniprot.org/uniprot/#_A0A0G2JGF1-mappedCitation-23935104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23935104 |
http://purl.uniprot.org/uniprot/#_Q15672-mappedCitation-23935104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23935104 |
http://purl.uniprot.org/uniprot/#_A2NV53-mappedCitation-23935104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23935104 |
http://purl.uniprot.org/uniprot/#_A0N0L5-mappedCitation-23935104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23935104 |
http://purl.uniprot.org/uniprot/#_B7ZC18-mappedCitation-23935104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23935104 |
http://purl.uniprot.org/uniprot/#_Q3ULI4-mappedCitation-23935104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23935104 |
http://purl.uniprot.org/uniprot/#_Q3U6S9-mappedCitation-23935104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23935104 |