| http://purl.uniprot.org/citations/23945946 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23945946 | http://www.w3.org/2000/01/rdf-schema#comment | "Ribosome biogenesis requires >300 assembly factors in Saccharomyces cerevisiae. Ribosome assembly factors Imp3, Mrt4, Rlp7 and Rlp24 have sequence similarity to ribosomal proteins S9, P0, L7 and L24, suggesting that these pre-ribosomal factors could be placeholders that prevent premature assembly of the corresponding ribosomal proteins to nascent ribosomes. However, we found L7 to be a highly specific component of Rlp7-associated complexes, revealing that the two proteins can bind simultaneously to pre-ribosomal particles. Cross-linking and cDNA analysis experiments showed that Rlp7 binds to the ITS2 region of 27S pre-rRNAs, at two sites, in helix III and in a region adjacent to the pre-rRNA processing sites C1 and E. However, L7 binds to mature 25S and 5S rRNAs and cross-linked predominantly to helix ES7(L)b within 25S rRNA. Thus, despite their predicted structural similarity, our data show that Rlp7 and L7 clearly bind at different positions on the same pre-60S particles. Our results also suggest that Rlp7 facilitates the formation of the hairpin structure of ITS2 during 60S ribosomal subunit maturation."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/gkt726"xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/author | "Namane A."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/author | "Jacquier A."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/author | "Fromont-Racine M."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/author | "Saveanu C."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/author | "Badis G."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/author | "de la Cruz J."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/author | "Doyen A."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/author | "Diaz-Quintana A."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/author | "Babiano R."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/name | "Nucleic Acids Res"xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/pages | "9461-9470"xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/title | "Yeast ribosomal protein L7 and its homologue Rlp7 are simultaneously present at distinct sites on pre-60S ribosomal particles."xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://purl.uniprot.org/core/volume | "41"xsd:string |
| http://purl.uniprot.org/citations/23945946 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23945946 |
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| http://purl.uniprot.org/uniprot/P40693#attribution-86CB324591FC85D40B4D3F9918999DE4 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23945946 |
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| http://purl.uniprot.org/uniprot/#_Q12213-mappedCitation-23945946 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23945946 |
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