| http://purl.uniprot.org/citations/23954298 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23954298 | http://www.w3.org/2000/01/rdf-schema#comment | "Enteropeptidase can cleave trypsinogen on the sequence of Asp-Asp-Asp-Asp-Lys and plays an important role in food digestion. The RANKL-RANK signalling pathway plays a pivotal role in bone remodelling. In this study, we reported that enteropeptidase can inhibit the RANKL-RANK signalling pathway through the cleavage of RANK. A surrogate peptide blocking assay indicated that enteropeptidase could specifically cleave RANK on the sequence NEEDK. Osteoclast differentiation assay and NF-κB activity assay confirmed that enteropeptidase could inhibit osteoclastogenesis in vitro through the cleavage of RANK. This is the first study to prove that the RANKL-RANK signalling pathway can be inhibited by cleavage of RANK instead of targeting RANKL."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2013.08.005"xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Chen Y."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Liu C."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Gao B."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Li W."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Jin M."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Ma J."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Zhang S."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Wang L."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Zhou Y."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Zhao Y."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Han H."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Niu G."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Tao H."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/author | "Tao H.'"xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/pages | "2958-2964"xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/title | "Inhibition effect of enteropeptidase on RANKL-RANK signalling by cleavage of RANK."xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://purl.uniprot.org/core/volume | "587"xsd:string |
| http://purl.uniprot.org/citations/23954298 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23954298 |
| http://purl.uniprot.org/citations/23954298 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23954298 |