http://purl.uniprot.org/citations/23962556 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23962556 | http://www.w3.org/2000/01/rdf-schema#comment | "The microRNA miR-101 has been reported to be a tumor suppressor. Here we show that low expression of miR-101 is associated with poor survival in stage IV melanoma patients. We identified microphthalmia-associated transcription factor (MITF) as a direct target of miR-101. In melanoma cells, overexpression of miR-101 downregulated protein levels of MITF and a previously reported target protein, enhancer of zeste homolog 2 (EZH2). Functional assays showed that miR-101 suppressed invasion and proliferation - an outcome that could be phenocopied by siRNA knockdown of MITF and EZH2. Our data suggest that miR-101 might have a beneficial role in melanoma."xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.canlet.2013.08.021"xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/author | "Chen Y."xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/author | "Luo C."xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/author | "Schadendorf D."xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/author | "Pscherer A."xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/author | "Merz P.R."xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/author | "Dickes E."xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/author | "Eichmuller S.B."xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/name | "Cancer Lett"xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/pages | "240-247"xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/title | "MiR-101 inhibits melanoma cell invasion and proliferation by targeting MITF and EZH2."xsd:string |
http://purl.uniprot.org/citations/23962556 | http://purl.uniprot.org/core/volume | "341"xsd:string |
http://purl.uniprot.org/citations/23962556 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23962556 |
http://purl.uniprot.org/citations/23962556 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23962556 |
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http://purl.uniprot.org/uniprot/#_A0A0A7NWS7-mappedCitation-23962556 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23962556 |
http://purl.uniprot.org/uniprot/#_B4DNC7-mappedCitation-23962556 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23962556 |
http://purl.uniprot.org/uniprot/#_B7Z8K5-mappedCitation-23962556 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23962556 |