| http://purl.uniprot.org/citations/23974364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23974364 | http://www.w3.org/2000/01/rdf-schema#comment | "Transglutaminase 4 has been shown to enhance various biological properties of prostate cancer cells, e.g., cell-matrix adhesion, invasiveness and the epithelial-mesenchymal transition. The objectives of this study were to investigate the associations between transglutaminase 4 expression and the established features and biochemical recurrence of prostate cancer. Transglutaminase 4 immunostaining was performed on a tissue microarray. The expression of transglutaminase 4 was evaluated by a scoring method based on the intensity and extent of staining. The clinical and pathological information was obtained through a review of medical records. Follow-up data were obtained by consulting the hospital medical records and the prostate cancer database of our department and by contacting patients or family members. We then compared the transglutaminase 4 expression levels between the prostate cancer tissues and the paracarcinoma tissues and evaluated the correlation of transglutaminase 4 expression with the clinical parameters and biochemical recurrence of prostate cancer. Our results indicated that the transglutaminase 4 staining was significantly higher in tumour tissue than in paracarcinoma tissue (P<0.001) and was positively associated with higher Gleason score (P<0.001) and higher prostate-specific antigen level (P=0.005). Patients with transglutaminase 4 overexpression experienced shorter biochemical recurrence-free survival after surgery (P=0.042) in the univariate analysis but not in the multivariate analysis (P=0.139), which indicated that transglutaminase 4 may serve as a potential predictor of biochemical recurrence of prostate cancer."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.org/dc/terms/identifier | "doi:10.1038/aja.2013.79"xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/author | "Cao Z."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/author | "Wang Y."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/author | "Sun Y.H."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/author | "Qiao M."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/author | "Liu Z.Y."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/author | "Zhang Z.S."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/author | "Ren S.C."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/author | "Yu Y.W."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/author | "Zhai B.B."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/name | "Asian J Androl"xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/pages | "742-746"xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/title | "Overexpression of transglutaminase 4 and prostate cancer progression: a potential predictor of less favourable outcomes."xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://purl.uniprot.org/core/volume | "15"xsd:string |
| http://purl.uniprot.org/citations/23974364 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23974364 |
| http://purl.uniprot.org/citations/23974364 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23974364 |
| http://purl.uniprot.org/uniprot/#_A0A994J576-mappedCitation-23974364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23974364 |
| http://purl.uniprot.org/uniprot/#_B2R7D1-mappedCitation-23974364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23974364 |
| http://purl.uniprot.org/uniprot/#_B4DU73-mappedCitation-23974364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23974364 |
| http://purl.uniprot.org/uniprot/#_B4YUQ1-mappedCitation-23974364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23974364 |
| http://purl.uniprot.org/uniprot/#_B4YUQ2-mappedCitation-23974364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23974364 |
| http://purl.uniprot.org/uniprot/#_B4YUQ3-mappedCitation-23974364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23974364 |