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http://purl.uniprot.org/citations/23993985http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23993985http://www.w3.org/2000/01/rdf-schema#comment"Susceptibility to myasthenia gravis (MG) has been demonstrated with several HLA in different disease subgroups. HLA-DR14, -DR16 and -DQ5 were reported as predisposing factors in muscle-specific kinase antibody positive MG (MuSK-MG). These markers were evaluated in MG subgroups from Turkey. Among 164 generalized MG patients, 116 had antibodies against anti-acetylcholine receptor (AChR-MG) and 48 had MuSK-MG. Only HLA-DRB1 and DQB1 allele groups reported to be associated with MuSK-MG were compared with 250 healthy controls (HC). Highly significant associations of both DRB1(∗)16 and DRB1(∗)14 were found with MuSK-MG compared to HC (p = 1.9 × 10(-5), OR: 4.95 and p = 0.0028, OR: 3.1). On the contrary, HLA-DRB1(∗)03 was less frequent in MuSK-MG (p = 0.006, OR: 0.09). DQB1(∗)05 was also associated with MuSK-MG (p = 2.5 × 10(-6) OR: 4.8). This study provides a replication of the highly significant associations of both HLA-DRB1(∗)16,-DRB1(∗)14 and -DQB1(∗)05 with MuSK-MG. Moreover, HLA-DRB1(∗)03 appears to have a distinguishing role for this disease subgroup compared to early-onset and AChR-MG."xsd:string
http://purl.uniprot.org/citations/23993985http://purl.org/dc/terms/identifier"doi:10.1016/j.humimm.2013.08.271"xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/author"Deymeer F."xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/author"Gulsen-Parman Y."xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/author"Saruhan-Direskeneli G."xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/author"Yilmaz V."xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/author"Oflazer P."xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/author"Alahgholi-Hajibehzad M."xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/author"Aysal F."xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/name"Hum Immunol"xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/pages"1633-1635"xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/title"Association of HLA-DRB1∗14, -DRB1∗16 and -DQB1∗05 with MuSK-myasthenia gravis in patients from Turkey."xsd:string
http://purl.uniprot.org/citations/23993985http://purl.uniprot.org/core/volume"74"xsd:string
http://purl.uniprot.org/citations/23993985http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23993985
http://purl.uniprot.org/citations/23993985http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23993985
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-23993985http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23993985
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-23993985http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23993985
http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-23993985http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23993985
http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-23993985http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23993985
http://purl.uniprot.org/uniprot/#_A0A0E3DC99-mappedCitation-23993985http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23993985
http://purl.uniprot.org/uniprot/#_A0A076L4M5-mappedCitation-23993985http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23993985
http://purl.uniprot.org/uniprot/#_A0A0A0WDZ3-mappedCitation-23993985http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23993985
http://purl.uniprot.org/uniprot/#_A0A0A7C7I5-mappedCitation-23993985http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23993985