| http://purl.uniprot.org/citations/24018270 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24018270 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24018270 | http://www.w3.org/2000/01/rdf-schema#comment | "Killer Ig-like receptors (KIRs) are innate immune receptors expressed by NK and T cells classically associated with the detection of missing self through loss of their respective MHC ligand. Some KIR specificities for allelic classical class I MHC (MHC-I) have been described, whereas other KIR receptor-ligand relationships, including those associated with nonclassical MHC-I, have yet to be clearly defined. We report in this article that KIR3DL2 and KIR2DS4 and the nonclassical Ag HLA-F, expressed as a free form devoid of peptide, physically and functionally interact. These interactions extend to include classical MHC-I open conformers as ligands, defining new relationships between KIR receptors and MHC-I. The data collectively suggest a broader, previously unrecognized interaction between MHC-I open conformers--including prototypical HLA-F--and KIR receptors, acting in an immunoregulatory capacity centered on the inflammatory response."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.1300081"xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.1300081"xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/author | "Lee N."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/author | "Lee N."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/author | "Geraghty D.E."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/author | "Geraghty D.E."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/author | "Burian A."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/author | "Burian A."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/author | "Goodridge J.P."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/author | "Goodridge J.P."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/pages | "3553-3562"xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/pages | "3553-3562"xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/title | "HLA-F and MHC class I open conformers are ligands for NK cell Ig-like receptors."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/title | "HLA-F and MHC class I open conformers are ligands for NK cell Ig-like receptors."xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/volume | "191"xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://purl.uniprot.org/core/volume | "191"xsd:string |
| http://purl.uniprot.org/citations/24018270 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24018270 |
| http://purl.uniprot.org/citations/24018270 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24018270 |