RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/24021649http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24021649http://www.w3.org/2000/01/rdf-schema#comment"Though the vascular endothelial growth factor coreceptor neuropilin-1 (Nrp1) plays a critical role in vascular development, its precise function is not fully understood. We identified a group of novel binding partners of the cytoplasmic domain of Nrp1 that includes the focal adhesion regulator, Filamin A (FlnA). Endothelial cells (ECs) expressing a Nrp1 mutant devoid of the cytoplasmic domain (nrp1(cyto)(Δ/Δ)) migrated significantly slower in response to VEGF relative to the cells expressing wild-type Nrp1 (nrp1(+/+) cells). The rate of FA turnover in VEGF-treated nrp1(cyto)(Δ/Δ) ECs was an order of magnitude lower in comparison to nrp1(+/+) ECs, thus accounting for the slower migration rate of the nrp1(cyto)(Δ/Δ) ECs."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2013.08.040"xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/author"Agrawal S."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/author"Buck M."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/author"Drazba J."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/author"Ruhrberg C."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/author"Horowitz A."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/author"Vasanji A."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/author"Kong N."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/author"Borthakur S."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/author"Fantin A."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/author"Seerapu H.R."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/pages"3392-3399"xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/title"The cytoplasmic domain of neuropilin-1 regulates focal adhesion turnover."xsd:string
http://purl.uniprot.org/citations/24021649http://purl.uniprot.org/core/volume"587"xsd:string
http://purl.uniprot.org/citations/24021649http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24021649
http://purl.uniprot.org/citations/24021649http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24021649
http://purl.uniprot.org/uniprot/#_O14786-mappedCitation-24021649http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24021649
http://purl.uniprot.org/uniprot/#_P10126-mappedCitation-24021649http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24021649
http://purl.uniprot.org/uniprot/#_Q3UFP7-mappedCitation-24021649http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24021649
http://purl.uniprot.org/uniprot/#_Q3UQY7-mappedCitation-24021649http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24021649
http://purl.uniprot.org/uniprot/#_P17182-mappedCitation-24021649http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24021649