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http://purl.uniprot.org/citations/24022884http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24022884http://www.w3.org/2000/01/rdf-schema#comment"In the mouse embryo and differentiating embryonic stem cells, the hematopoietic, endothelial, and cardiomyocyte lineages are derived from Flk1+ mesodermal progenitors. Here, we report that surface expression of Podocalyxin (Podxl), a member of the CD34 family of sialomucins, can be used to subdivide the Flk1+ cells in differentiating embryoid bodies at day 4.75 into populations that develop into distinct mesodermal lineages. Definitive hematopoietic potential was restricted to the Flk1+Podxl+ population, while the Flk1-negative Podxl+ population displayed only primitive erythroid potential. The Flk1+Podxl-negative population contained endothelial cells and cardiomyocyte potential. Podxl expression distinguishes Flk1+ mesoderm populations in mouse embryos at days 7.5, 8.5, and 9.5 and is a marker of progenitor stage primitive erythroblasts. These findings identify Podxl as a useful tool for separating distinct mesodermal lineages."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.org/dc/terms/identifier"doi:10.1002/stem.1536"xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/author"Zhang H."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/author"Isern J."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/author"Lemischka I.R."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/author"Dyer M.A."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/author"Baron M.H."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/author"Papatsenko D."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/author"Fraser S.T."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/author"D'Souza S.L."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/author"Douvaras P."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/author"Nieves J.L."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/name"Stem Cells"xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/pages"191-203"xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/title"Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm."xsd:string
http://purl.uniprot.org/citations/24022884http://purl.uniprot.org/core/volume"32"xsd:string
http://purl.uniprot.org/citations/24022884http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24022884
http://purl.uniprot.org/citations/24022884http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24022884
http://purl.uniprot.org/uniprot/#_Q3UYF4-mappedCitation-24022884http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24022884
http://purl.uniprot.org/uniprot/#_Q791G4-mappedCitation-24022884http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24022884
http://purl.uniprot.org/uniprot/#_Q9R0M4-mappedCitation-24022884http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24022884
http://purl.uniprot.org/uniprot/Q3UYF4http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24022884
http://purl.uniprot.org/uniprot/Q791G4http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24022884