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http://purl.uniprot.org/citations/2402637http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2402637http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2402637http://www.w3.org/2000/01/rdf-schema#comment"The primary structure of lipopolysaccharide binding protein (LBP), a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides (LPSs), was deduced by sequencing cloned complementary DNA. LBP shares sequence identity with another LPS binding protein found in granulocytes, bactericidal/permeability-increasing protein, and with cholesterol ester transport protein of the plasma. LBP may control the response to LPS under physiologic conditions by forming high-affinity complexes with LPS that bind to monocytes and macrophages, which then secrete tumor necrosis factor. The identification of this pathway for LPS-induced monocyte stimulation may aid in the development of treatments for diseases in which Gram-negative sepsis or endotoxemia are involved."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.org/dc/terms/identifier"doi:10.1126/science.2402637"xsd:string
http://purl.uniprot.org/citations/2402637http://purl.org/dc/terms/identifier"doi:10.1126/science.2402637"xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Wright S.D."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Wright S.D."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Gray P.W."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Gray P.W."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Leong S.R."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Leong S.R."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Ulevitch R.J."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Ulevitch R.J."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Mathison J.C."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Mathison J.C."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Tobias P.S."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Tobias P.S."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Flaggs G.W."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Flaggs G.W."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Schumann R.R."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/author"Schumann R.R."xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/2402637http://purl.uniprot.org/core/name"Science"xsd:string