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http://purl.uniprot.org/citations/24032687http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24032687http://www.w3.org/2000/01/rdf-schema#comment"To determine whether caveolae and caveolin-1 affect the distribution of calcitonin receptor-like receptors (CLR) in vascular smooth muscle cell (VSMC) membranes, we have used VSMCs cell line A10. We found that calcitonin gene-related peptide (CGRP) reduced CLR protein in the VSMC membrane in a time-dependent manner, which was dramatically decreased after 4 h CGRP treatment, and remained at a low level after 16 h. CGRP8-37 or β-cyclodextrin (β-CD) blocked this effect, without changing the total levels of CLR protein and mRNA in the cells. Co-immunoprecipitation experiments showed that CLR bound to caveolin-1 in cell membrane fractions. Confocal laser microscopic studies confirmed this co-localization relationship at the cell plasma membrane. Thus, our data indicate that the structural integrity of caveolae plays an important role in regulating subcellular distribution of CLR."xsd:string
http://purl.uniprot.org/citations/24032687http://purl.org/dc/terms/identifier"doi:10.1139/bcb-2013-0020"xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/author"Chen L.X."xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/author"Zhang L."xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/author"Sun F."xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/author"Tang J.Q."xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/author"Wang Y.H."xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/author"Fu X.Q."xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/author"Yao C.H."xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/author"Qin X.P."xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/name"Biochem Cell Biol"xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/pages"357-360"xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/title"The role of caveolae in regulating calcitonin receptor-like receptor subcellular distribution in vascular smooth muscle cells."xsd:string
http://purl.uniprot.org/citations/24032687http://purl.uniprot.org/core/volume"91"xsd:string
http://purl.uniprot.org/citations/24032687http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24032687
http://purl.uniprot.org/citations/24032687http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24032687
http://purl.uniprot.org/uniprot/#_A2AR99-mappedCitation-24032687http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24032687
http://purl.uniprot.org/uniprot/#_Q9R1W5-mappedCitation-24032687http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24032687
http://purl.uniprot.org/uniprot/Q9R1W5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24032687
http://purl.uniprot.org/uniprot/A2AR99http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24032687