RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/24033735http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24033735http://www.w3.org/2000/01/rdf-schema#comment"

Aim

To assess the association between the human leukocyte antigen system and retinopathy of prematurity.

Methods

Neonates of <32 weeks of gestational age, born at two level III neonatal intensive care units from January 2000 to December 2001 and from January 2006 to June 2009, were included in the study. Demographic and clinical data were recorded, and retinopathy was classified according to the International Classification. Epithelial cells were collected from the oral cavity and the HLA were studied using the PCR/SSO method. Univariate and multivariate analyses were performed using SPSS® v.18.

Results

We evaluated 156 neonates, including 82 (52.6%) males. Median gestational age was 29 (23-31) weeks, and median birth weight was 1030 (525-1935) grams. Seventy (44.9%) of the neonates developed retinopathy. Alleles HLA-B*38, HLA-Cw*12, HLA-DRB1*09, HLA-DRB1*14 (univariate analysis) and HLA-A*68 and HLA-Cw*12 were associated to retinopathy (multivariate analysis).

Conclusion

The results suggest that the HLA system may be associated with the development of retinopathy of prematurity. A large-scale population-based study should be performed to clarify this association."xsd:string
http://purl.uniprot.org/citations/24033735http://purl.org/dc/terms/identifier"doi:10.1111/apa.12410"xsd:string
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/author"Freitas F."xsd:string
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/author"Rocha G."xsd:string
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/author"Tafulo S."xsd:string
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/author"Guimaraes H."xsd:string
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/author"Proenca E."xsd:string
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/author"Flor-de-Lima F."xsd:string
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/name"Acta Paediatr"xsd:string
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/pages"1150-1153"xsd:string
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/title"The role of the human leukocyte antigen system in retinopathy of prematurity: a pilot study."xsd:string
http://purl.uniprot.org/citations/24033735http://purl.uniprot.org/core/volume"102"xsd:string
http://purl.uniprot.org/citations/24033735http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24033735
http://purl.uniprot.org/citations/24033735http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24033735
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-24033735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24033735
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-24033735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24033735
http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-24033735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24033735
http://purl.uniprot.org/uniprot/#_A0A0A7C543-mappedCitation-24033735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24033735
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-24033735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24033735
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-24033735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24033735
http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-24033735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24033735
http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-24033735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24033735
http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-24033735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24033735