http://purl.uniprot.org/citations/24047646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/24047646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/24047646 | http://www.w3.org/2000/01/rdf-schema#comment | "Cells sense their size and use this information to coordinate cell division with cell growth to maintain a constant cell size within a given population. A model has been proposed for cell size control in the rod-shaped cells of the fission yeast, Schizosaccharomyces pombe. This involves a protein localized to the cell ends, which inhibits mitotic activators in the middle of the cell in a cell size-dependent manner. This protein, Pom1, along with another tip-localized protein, Nif1, have been implicated as direct sensors of cell size controlling the onset of mitosis. Here we have investigated cell size variability and size homeostasis at the G 2/M transition, focusing on the role of pom1 and nif1. Cells deleted for either of these 2 genes show wild-type size homeostasis both in size variability analyses and size homeostasis experiments. This indicates that these genes do not have a critical role as direct cell size sensors in the control mechanism. Cell size homeostasis also seems to be independent of Cdc2-Tyr15 phosphorylation, suggesting that the size sensing mechanism in fission yeast may act through an unidentified pathway regulating CDK activity by an unknown mechanism."xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.org/dc/terms/identifier | "doi:10.4161/cc.26462"xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.org/dc/terms/identifier | "doi:10.4161/cc.26462"xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/author | "Nurse P."xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/author | "Nurse P."xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/author | "Wood E."xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/author | "Wood E."xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/name | "Cell Cycle"xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/name | "Cell Cycle"xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/pages | "3228-3236"xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/pages | "3228-3236"xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/title | "Pom1 and cell size homeostasis in fission yeast."xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/title | "Pom1 and cell size homeostasis in fission yeast."xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/volume | "12"xsd:string |
http://purl.uniprot.org/citations/24047646 | http://purl.uniprot.org/core/volume | "12"xsd:string |
http://purl.uniprot.org/citations/24047646 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24047646 |
http://purl.uniprot.org/citations/24047646 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24047646 |
http://purl.uniprot.org/citations/24047646 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24047646 |
http://purl.uniprot.org/citations/24047646 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24047646 |
http://purl.uniprot.org/uniprot/Q09690 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/24047646 |
http://purl.uniprot.org/uniprot/P87159#attribution-747307D2391DE75F89E78E91DD276596 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24047646 |