http://purl.uniprot.org/citations/24051655 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/24051655 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/24051655 | http://www.w3.org/2000/01/rdf-schema#comment | "Auxin is a major plant hormone that controls most aspects of plant growth and development. Auxin is perceived by two distinct classes of receptors: transport inhibitor response 1 (TIR1, or auxin-related F-box (AFB)) and auxin/indole-3-acetic acid (AUX/IAA) coreceptors, that control transcriptional responses to auxin, and the auxin-binding protein 1 (ABP1), that controls a wide variety of growth and developmental processes. To date, the mode of action of ABP1 is still poorly understood and its functional interaction with TIR1/AFB-AUX/IAA coreceptors remains elusive. Here we combine genetic and biochemical approaches to gain insight into the integration of these two pathways. We find that ABP1 is genetically upstream of TIR1/AFBs; ABP1 knockdown leads to an enhanced degradation of AUX/IAA repressors, independently of its effects on endocytosis, through the SCF(TIR1/AFB) E3 ubiquitin ligase pathway. Combining positive and negative regulation of SCF ubiquitin-dependent pathways might be a common mechanism conferring tight control of hormone-mediated responses."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncomms3496"xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncomms3496"xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Genschik P."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Genschik P."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Lechner E."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Lechner E."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Muller P."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Muller P."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Paque S."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Paque S."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Perrot-Rechenmann C."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Perrot-Rechenmann C."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Quettier A.L."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Quettier A.L."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Stierle V."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Stierle V."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Tromas A."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/author | "Tromas A."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/name | "Nat. Commun."xsd:string |
http://purl.uniprot.org/citations/24051655 | http://purl.uniprot.org/core/name | "Nat. Commun."xsd:string |