| http://purl.uniprot.org/citations/24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24058701 | http://www.w3.org/2000/01/rdf-schema#comment | "The unfolded protein response (UPR) is a collection of pathways that maintains the protein secretory pathway during the many physiological and pathological conditions that cause stress in the endoplasmic reticulum (ER). The UPR is mediated in part by Ire1, an ER transmembrane kinase and endoribonuclease that is activated when misfolded proteins accumulate in the ER. Ire1's nuclease initiates the cytosolic splicing of the mRNA encoding X-box binding protein (Xbp1), a potent transcription factor that then upregulates genes responsible for restoring ER function. This same nuclease is responsible for the degradation of many other mRNAs that are localized to the ER, through Regulated Ire1 Dependent Decay (RIDD). Here we show that Smt3, a homolog of small ubiquitin-like modifier (sumo), is a non-canonical RIDD target in Drosophila S2 cells. Unlike other RIDD targets, the sumo transcript does not stably associate with the ER membrane, but instead relies on an Xbp1-like stem loop and a second UPR mediator, Perk, for its degradation during stress."xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0075723"xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://purl.uniprot.org/core/author | "Moore K.A."xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://purl.uniprot.org/core/author | "Hollien J."xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://purl.uniprot.org/core/author | "Craft J."xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://purl.uniprot.org/core/author | "Gaddam D."xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://purl.uniprot.org/core/author | "Plant J.J."xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24058701 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://purl.uniprot.org/core/pages | "e75723"xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://purl.uniprot.org/core/title | "Regulation of sumo mRNA during endoplasmic reticulum stress."xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/24058701 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24058701 |
| http://purl.uniprot.org/citations/24058701 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24058701 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KG56-mappedCitation-24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24058701 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KGJ5-mappedCitation-24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24058701 |
| http://purl.uniprot.org/uniprot/#_A8JR46-mappedCitation-24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24058701 |
| http://purl.uniprot.org/uniprot/#_D5AEM9-mappedCitation-24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24058701 |
| http://purl.uniprot.org/uniprot/#_P41374-mappedCitation-24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24058701 |
| http://purl.uniprot.org/uniprot/#_F3YDH0-mappedCitation-24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24058701 |
| http://purl.uniprot.org/uniprot/#_O97102-mappedCitation-24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24058701 |
| http://purl.uniprot.org/uniprot/#_O97365-mappedCitation-24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24058701 |
| http://purl.uniprot.org/uniprot/#_Q24093-mappedCitation-24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24058701 |
| http://purl.uniprot.org/uniprot/#_Q9VUB9-mappedCitation-24058701 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24058701 |