RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/24078449http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24078449http://www.w3.org/2000/01/rdf-schema#comment"Vascular endothelial growth factor-C (VEGF-C) is considered as a prime mediator of lymphangiogenesis and has been implicated in carcinogenesis and metastasis. Various studies examined the relationship between VEGF-C protein overexpression with the clinical outcome in patients with breast cancer but yielded conflicting results. Electronic databases updated to April 2013 were searched to find relevant studies. A meta-analysis was conducted with eligible studies which quantitatively evaluated the relationship between VEGF-C overexpression and survival of patients with breast cancer. Survival data were aggregated and quantitatively analyzed. We performed a meta-analysis of 11 studies (n = 1,357 patients) that evaluated the correlation between VEGF-C overexpression detected by immunohistochemistry and survival in patients with breast cancer. Combined hazard ratios suggested that VEGF-C overexpression was not associated with poor prognosis of disease-free survival (HR [hazard ratio] = 0.80, 95 % CI [confidence interval]: 0.51-1.09), overall survival (OS) (HR = 1.08, 95 % CI: 0.37-1.78) in patients with breast cancer. In the stratified analysis by patient source, significantly risks were not found among Asians or non-Asians. No significant heterogeneity was observed among all studies. VEGF-C overexpression was not associated with poor disease-free survival or overall survival in breast cancer."xsd:string
http://purl.uniprot.org/citations/24078449http://purl.org/dc/terms/identifier"doi:10.1007/s13277-013-1211-3"xsd:string
http://purl.uniprot.org/citations/24078449http://purl.uniprot.org/core/author"Lu C."xsd:string
http://purl.uniprot.org/citations/24078449http://purl.uniprot.org/core/author"Gao S."xsd:string
http://purl.uniprot.org/citations/24078449http://purl.uniprot.org/core/author"Ma J.J."xsd:string
http://purl.uniprot.org/citations/24078449http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24078449http://purl.uniprot.org/core/name"Tumour Biol"xsd:string
http://purl.uniprot.org/citations/24078449http://purl.uniprot.org/core/pages"1523-1529"xsd:string
http://purl.uniprot.org/citations/24078449http://purl.uniprot.org/core/title"Prognostic significance of VEGF-C immunohistochemical expression in breast cancer: a meta-analysis."xsd:string
http://purl.uniprot.org/citations/24078449http://purl.uniprot.org/core/volume"35"xsd:string
http://purl.uniprot.org/citations/24078449http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24078449
http://purl.uniprot.org/citations/24078449http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24078449
http://purl.uniprot.org/uniprot/#_P49767-mappedCitation-24078449http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24078449
http://purl.uniprot.org/uniprot/#_Q6FH59-mappedCitation-24078449http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24078449
http://purl.uniprot.org/uniprot/P49767http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24078449
http://purl.uniprot.org/uniprot/Q6FH59http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24078449