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| http://purl.uniprot.org/citations/24090997 | http://www.w3.org/2000/01/rdf-schema#comment | "NUP98 is among the most promiscuously translocated genes in hematological diseases. Among the 28 known fusion partners, there are two categories: homeobox genes and non-homeobox genes. The homeobox fusion partners are well-studied in animal models, resulting in HoxA cluster overexpression and hematological disease. The non-homeobox fusion partners are less well studied. We created transgenic animal models for three NUP98 fusion genes (one homeobox, two non-homeobox), and show that in this system, the NUP98-homeobox fusion promotes self-renewal and aberrant gene expression to a significantly greater extent. We conclude that homeobox partners create more potent NUP98 fusion oncogenes than do non-homeobox partners."xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.leukres.2013.09.013"xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/author | "Saw J."xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/author | "Aplan P.D."xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/author | "Dobrovic A."xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/author | "Hussey D.J."xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/author | "Curtis D.J."xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/author | "Slape C.I."xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/name | "Leuk Res"xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/pages | "1668-1673"xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/title | "The fusion partner specifies the oncogenic potential of NUP98 fusion proteins."xsd:string |
| http://purl.uniprot.org/citations/24090997 | http://purl.uniprot.org/core/volume | "37"xsd:string |
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