| http://purl.uniprot.org/citations/24105263 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24105263 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24105263 | http://www.w3.org/2000/01/rdf-schema#comment | "Inter-organelle membrane contacts sites (MCSs) are specific subcellular regions favoring the exchange of metabolites and information. We investigated the potential role of the late-endosomal membrane-anchored proteins StAR related lipid transfer domain-3 (STARD3) and STARD3 N-terminal like (STARD3NL) in the formation of MCSs involving late-endosomes (LEs). We demonstrate that both STARD3 and STARD3NL create MCSs between LEs and the endoplasmic reticulum (ER). STARD3 and STARD3NL use a conserved two phenylalanines in an acidic tract (FFAT)-motif to interact with ER-anchored VAP proteins. Together, they form an LE-ER tethering complex allowing heterologous membrane apposition. This LE-ER tethering complex affects organelle dynamics by altering the formation of endosomal tubules. An in situ proximity ligation assay between STARD3, STARD3NL and VAP proteins identified endogenous LE-ER MCS. Thus, we report here the identification of proteins involved in inter-organellar interaction."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.org/dc/terms/identifier | "doi:10.1242/jcs.139295"xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.org/dc/terms/identifier | "doi:10.1242/jcs.139295"xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Kessler P."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Kessler P."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Rousseau A."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Rousseau A."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Stoll I."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Stoll I."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Levine T.P."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Levine T.P."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Schwab Y."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Schwab Y."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Alpy F."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Alpy F."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Rio M.C."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Rio M.C."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Tomasetto C."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Tomasetto C."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Wendling C."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Wendling C."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Mathelin C."xsd:string |
| http://purl.uniprot.org/citations/24105263 | http://purl.uniprot.org/core/author | "Mathelin C."xsd:string |