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http://purl.uniprot.org/citations/24117492http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24117492http://www.w3.org/2000/01/rdf-schema#comment"The enzyme myo-inositol oxygenase is the key enzyme of a pathway leading from myo-inositol to UDP-glucuronic acid. In Arabidopsis, myo-inositol oxygenase is encoded by four genes. All genes are strongly expressed in syncytia induced by the beet cyst nematode Heterodera schachtii in Arabidopsis roots. Here, we studied the effect of a quadruple myo-inositol oxygenase mutant on nematode development. We performed metabolite profiling of syncytia induced in roots of the myo-inositol oxygenase quadruple mutant. The role of galactinol in syncytia was studied using Arabidopsis lines with elevated galactinol levels and by supplying galactinol to wild-type seedlings. The quadruple myo-inositol oxygenase mutant showed a significant reduction in susceptibility to H. schachtii, and syncytia had elevated myo-inositol and galactinol levels and an elevated expression level of the antimicrobial thionin gene Thi2.1. This reduction in susceptibility could also be achieved by exogenous application of galactinol to wild-type seedlings. The primary function of myo-inositol oxygenase for syncytium development is probably not the production of UDP-glucuronic acid as a precursor for cell wall polysaccharides, but the reduction of myo-inositol levels and thereby a reduction in the galactinol level to avoid the induction of defence-related genes."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.org/dc/terms/identifier"doi:10.1111/nph.12535"xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/author"Weckwerth W."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/author"Tenhaken R."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/author"Endres S."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/author"Bohlmann H."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/author"Grundler F.M.W."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/author"Siddique S."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/author"Sobczak M."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/author"Radakovic Z.S."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/author"Fragner L."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/name"New Phytol"xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/pages"476-485"xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/title"Myo-inositol oxygenase is important for the removal of excess myo-inositol from syncytia induced by Heterodera schachtii in Arabidopsis roots."xsd:string
http://purl.uniprot.org/citations/24117492http://purl.uniprot.org/core/volume"201"xsd:string
http://purl.uniprot.org/citations/24117492http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24117492
http://purl.uniprot.org/citations/24117492http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24117492
http://purl.uniprot.org/uniprot/#_A0A1P8APC9-mappedCitation-24117492http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24117492
http://purl.uniprot.org/uniprot/#_A0A1P8BGX3-mappedCitation-24117492http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24117492
http://purl.uniprot.org/uniprot/#_B4F7Q2-mappedCitation-24117492http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24117492
http://purl.uniprot.org/uniprot/#_F4HW72-mappedCitation-24117492http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24117492
http://purl.uniprot.org/uniprot/#_O82200-mappedCitation-24117492http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24117492
http://purl.uniprot.org/uniprot/#_Q8L799-mappedCitation-24117492http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24117492